Intra-arterial Pump Infusional Chemotherapy

Reference work entry


Intra-arterial infusion chemotherapy has a long history since 1950s, and it has been performed with surgical catheter and pump implantation. The percutaneous approach has been developed with techniques of interventional radiology since 1980s. Interventional radiology can provide minimally invasive and accurate intra-arterial infusion chemotherapy consisted of arterial redistribution, percutaneous catheter placement, and drug distribution management. With these techniques, some small studies showed promising data especially in the treatment of liver metastases, but any larger study has not been done yet. Since modern systemic chemotherapy is well advanced, the role of intra-arterial infusion chemotherapy is not much recognized in the field of medical oncology. However, intra-arterial infusion chemotherapy cannot be done without accurate knowledge and techniques. To evaluate this treatment modality correctly at the present and to decide the new role of intra-arterial infusion chemotherapy, interventional radiologists should understand their very important role on intra-arterial infusion chemotherapy.


Hepatic Artery Drug Distribution Common Hepatic Artery Indwell Catheter Infusion Chemotherapy 
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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyNational Cancer Center HospitalTokyoJapan

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