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Imaging of Interventional Therapies in Oncology: Ultrasound

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Image-Guided Cancer Therapy

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Abstract

Ultrasonography (US) and contrast-enhanced ultrasonography (CEUS) play a key role at each step of imaging-guided therapies. Ultrasound (US) is actually the most widely diffused imaging technique for the guidance of percutaneous ablation as it allows for real-time visualization of the ablation device insertion and monitoring of the procedure and does not require ionizing radiation.

CEUS allows to diagnose focal lesions on the basis of enhancement patterns that are analogous to those typically seen on contrast-enhanced CT and MRI. Compared to CT and MRI, CEUS has the limitation to enable the study of one lesion at a time, but it has the advantage to be a real-time technique. CEUS is usefully employed before ablation for detection and characterization of lesions, pre-procedure planning, intra-procedure targeting (particularly for difficult and/or small lesions) and monitoring and, immediately after ablation, correct assessment of the volume of necrosis achieved, and detection of possible residual foci of untreated tumor.

CEUS can also implement B-mode US when real-time US-CT/MRI fusion imaging (or “virtual navigation”) is employed: Real-time US is co-registered with previously acquired contrast-enhanced CT or MRI scans multiplanarly reconstructed and transferred to the US machine.

In conclusion, for interventional therapies of lesions and organs that can be imaged with US, CEUS is a very valuable tool in all the phases of treatments. When follow-up contrast-enhanced CT or MRI are contraindicated or not conclusive, CEUS can also be used in follow-up protocols.

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Author information

Authors and Affiliations

  1. Department of Diagnostic Imaging and Interventional Oncologic Radiology, General Hospital of Busto Arsizio, Piazzale Solaro, 3, Busto Arsizio, 21052, VA, Italy

    Luigi Solbiati

  2. Department of Biomedical Sciences and Technologies, Section of Radiological Science, School of Medicine, University of Milan, Via di Rudinì 8, Milan, 20142, MI, Italy

    Tania Tondolo

Authors
  1. Luigi Solbiati
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  2. Tania Tondolo
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Corresponding author

Correspondence to Luigi Solbiati .

Editor information

Editors and Affiliations

  1. The Warren Alpert Medical School of Brown University, Department of Diagnostic Imaging Rhode Island Hospital, Providence, Rhode Island, USA

    Damian E. Dupuy

  2. Department of Surgery and Radiology Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    Yuman Fong

  3. McMullen Consulting, LLC, Surprise, Arizona, USA

    William N. McMullen

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© 2013 Springer Science+Business Media New York

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Solbiati, L., Tondolo, T. (2013). Imaging of Interventional Therapies in Oncology: Ultrasound. In: Dupuy, D., Fong, Y., McMullen, W. (eds) Image-Guided Cancer Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0751-6_15

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  • DOI: https://doi.org/10.1007/978-1-4419-0751-6_15

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0750-9

  • Online ISBN: 978-1-4419-0751-6

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