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11C: Labeling Chemistry and Labeled Compounds

  • G. Antoni
  • T. Kihlberg
  • B. Långström

Abstract

Methods for the synthesis of compounds labeled with the short-lived positron emitting radionuclide 11C are described. Important aspects on how to achieve high specific radioactivity and the need for technical solutions to establish a reproducible routine tracer production are pointed out. Examples of positron emission tomography (PET) as a tool in drug development are also included.

Keywords

Positron Emission Tomography Methyl Iodide Specific Radioactivity Positron Emission Tomography Data Radiochemical Yield 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  1. 1.Uppsala UniversityUppsalaSweden
  2. 2.Department of Biochemistry and Organic ChemistryUppsala UniversityUppsalaSweden

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