Reactor-Produced Medical Radionuclides

  • S. Mirzadeh
  • L. F. Mausner
  • M. A. Garland


The therapeutic use of radionuclides in nuclear medicine, oncology, and cardiology is the most rapidly growing use of medical radionuclides. Since most therapeutic radionuclides are neutron rich and decay by β emission, they are reactor-produced. This chapter deals mainly with production approaches with neutrons. Neutron interactions with matter, neutron transmission and activation rates, and neutron spectra of nuclear reactors are discussed in some detail. Further, a short discussion of the neutron-energy dependence of cross sections, reaction rates in thermal reactors, cross section measurements and flux monitoring, and general equations governing the reactor production of radionuclides are presented. Finally, the chapter is concluded by providing a number of examples encompassing the various possible reaction routes for the production of a number of medical radionuclides in a reactor.


Neutron Flux Neutron Energy Neutron Capture Capture Cross Section Activation Cross Section 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Research at ORNL was supported by the U.S. DOE under contract DE-AC05-00OR22725 with UT-Battelle, LLC. Research at BNL was supported by the U.S. DOE under Contract DE-AC02-98CH10886 with Brookhaven Science Associates.


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  1. 1.Oak Ridge National LaboratoryOak RidgeUSA
  2. 2.Brookhaven National LaboratoryUptonUSA

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