FSH (follicle stimulating hormone or follitropin, 2p21-p16)
FSH controls ovarian follicles, estrogen secretion, menstrual cycles, spermatogenesis, and D2 cyclin. Ovarian and testicular tumors have high levels of cyclin D mRNA. FSH deficient males have small testes, yet fertile to a variable degree. The 54-kb gene has 10 exons and encodes the 695-amino acid protein. animal hormone, follicle, ovary, menstruation, gametogenesis, differentiation, NGFI-A, cell cycle, gonadal dysgenesis; Driancourt MA 2001 Theriogenology 55:1211; FSH structure: Fan QR, Hendrickson WA 2005 Nature [Lond] 433:269.