Sickle Cell Trait

Reference work entry
DOI: https://doi.org/10.1007/978-1-4020-6754-9_15588

The sickle cell trait is due to heterozygosity of the recessive mutation in the gene controlling the β-chain of hemoglobin. Normally, these heterozygotes do not suffer from this condition but under low oxygen supply, e.g., at high elevations, adverse consequences may arise.  sickle cell anemia,  hemoglobin

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