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Represents the growing region of the DNA where the strands are temporarily separated. The simplest diagram of the replication fork is reproduced here showing the new (thin line) facing the polymerase with the 3′ end. The leading strand is below and the lagging strand is above (see Fig. R39). Replication is a very complex process requiring two different polymerases (δ and α for the leading and lagging strand, respectively) and several proteins. DNA replication eukaryotes, chart, DNA replication prokaryotes, nucleoid, GP32 protein, PriA, replication bubble, replication bidirectional, replication licensing, primase, Okazaki fragment, alpha accessory protein, processivity, replication machine; Waga S, Stillman B 1998 Annu Rev Biochem 67:721.

Figure R39.
figure 39

Replication fork

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(2008). Replication Fork. In: Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6754-9_14419

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