The protein likelihood method is used to determine evolutionary distance when the organisms are not closely related and when the non-synonymous base substitutions are higher than the synonymous ones. In such cases, the protein method may provide more reliable information. evolutionary distance, evolutionary tree, least square methods, four-cluster analysis, un-rooted evolutionary trees, transformed distance, Fitch-Margoliash test, DNA likelihood method; Whelan S Goldman N 2001 Mol Biol Evol 18:691.
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(2008). Protein Likelihood Method. In: Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6754-9_13620
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DOI: https://doi.org/10.1007/978-1-4020-6754-9_13620
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