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Social Support and Cardiovascular Disease

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Handbook of Cardiovascular Behavioral Medicine

Abstract

A growing body of research has demonstrated a strong and consistent association between lack of social support and cardiovascular disease (CVD) risk, progression, and outcomes. Low social support – variously defined as having few social ties, not having access to practical assistance, or lacking a confidant or other source of emotional support – has been linked to cardiovascular events and death in a number of large-scale, prospective studies of initially healthy persons and in studies of individuals with existing heart disease. Recently, research has identified a number of plausible psychophysiologic and behavioral mechanisms that may contribute to this relationship, and several intervention studies designed to improve cardiovascular-related health outcomes by increasing social support have been conducted. Here, we review evidence that social support influences the occurrence, course and outcomes of CVD; identify the mechanisms through which this may occur; review the results of intervention studies designed to increase social support and improve medical outcomes in CVD patients; and provide recommendations to researchers to guide future work in this area.

This chapter has been adapted from Czajkowski, Arteaga, and Burg (2011). The views expressed are those of the authors and do not reflect the views of the National Heart, Lung, and Blood Institute, National Institutes of Health, or the US Department of Health and Human Services.

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References

  1. Aggarwal BAF, Liao M, Mosca L (2008) Physical activity as a potential mechanism through which social support may reduce cardiovascular disease risk. J Cardiovasc Nurs 23:90–96

    Article  Google Scholar 

  2. Andre-Petersson L, Engstrom G, Hedblad B, Janzon L, Rosvall M (2007) Social support at work and the risk of myocardial infarction and stroke in women and men. Soc Sci Med 64:830–841

    Article  PubMed  Google Scholar 

  3. Barrera MJ, Sandler IN, Ramsey TB (1981) Preliminary development of a scale of social support: studies of college students. Am J Community Psychol 9:435–447

    Article  Google Scholar 

  4. Berkman LF (1984) Assessing the physical health effects of social networks and social support. Annu Rev Public Health 6:413–432

    Article  Google Scholar 

  5. Berkman LF, Syme SL (1979) Social networks, host resistance, and mortality. Am J Epidemiol 109:186–204

    Article  PubMed  Google Scholar 

  6. Berkman LF, Leo-Summers L, Horwitz RI (1992) Emotional support and survival after myocardial infarction: a prospective, population-based study of the elderly. Ann Intern Med 117:1003–1009

    Article  PubMed  Google Scholar 

  7. Berkman LF, Glass T, Brissette I, Seeman TE (2000) From social integration to health: Durkheim in the new millennium. Soc Sci Med 51:843–857

    Article  PubMed  Google Scholar 

  8. Blakely TA, Kennedy BP, Kawachi I (2001) Socioeconomic inequality in voting participation and self-rated health. Am J Public Health 99:99–104

    Google Scholar 

  9. Brook RD, Julius S (2000) Autonomic imbalance, hypertension, and cardiovascular risk. Am J Hypertens 13:1–122S

    Article  Google Scholar 

  10. Brummett BH, Barefoot JC, Siegler IC, Clapp-Channing NE, Lytle BL, Bosworth HB, Williams RB, Mark DB (2001) Characteristics of socially isolated patients with coronary artery disease who are at elevated risk for mortality. Psychosom Med 63:267–272

    Article  PubMed  Google Scholar 

  11. Burg MM, Barefoot J, Berkman L, Catellier DJ, Czajkowski S, Saab P, Huber M, Delillo V, Mitchell P, Skala J, Taylor CB (2005) Low perceived social support and post–myocardial infarction prognosis in the enhancing recovery in coronary heart disease clinical trial: the effects of treatment. Psychosom Med 67:879–888

    Article  PubMed  Google Scholar 

  12. Case RB, Moss AJ, Case N, McDermott M, Eberly S (1992) Living alone after myocardial infarction: impact on prognosis. JAMA 267:515–519

    Article  PubMed  Google Scholar 

  13. Chandra V, Szklo M, Goldberg R, Tonascia J (1983) The impact of marital status on survival after an acute myocardial infarction: a population-based study. Am J Epidemiol 117:320–332

    Article  PubMed  Google Scholar 

  14. Chin MH, Goldman L (1997) Correlates of early hospital readmission or death in patients with congestive heart failure. Am J Cardiol 79:1640–1644

    Article  PubMed  Google Scholar 

  15. Christakis N, Fowler JH (2007) The spread of obesity on a large social network over 32 years. N Engl J Med 357:370–379

    Article  PubMed  Google Scholar 

  16. Christakis N, Fowler JH (2008) The collective dynamics of smoking in a large social network. N Engl J Med 358:2249–2258

    Article  PubMed  PubMed Central  Google Scholar 

  17. Cohen S, Hoberman HM (1983) Positive events and social supports as buffers of life change stress. J Appl Soc Psychol 13:99–125

    Article  Google Scholar 

  18. Cohen S, Mermelstein R, Kamarck T, Hoberman H (1985) Measuring the functional components of social support. In: Sarason IG, Sarason BR (eds) Social support: theory research and application. Martinus Niijhoff, The Hague

    Google Scholar 

  19. Cohen S, Doyle WJ, Skoner DP, Rabin BS, Gwaltney JM (1997) Social ties and susceptibility to the common cold. JAMA 277:1940–1944

    Article  PubMed  Google Scholar 

  20. Cohen S, Underwood LG, Gottlieb BH (2000) Social support measurement and intervention: a guide for health and social scientists. Oxford University Press, New York

    Book  Google Scholar 

  21. Costanzo ES, Lutgendorf SK, Sood AK, Anderson B, Sorosky J, Lubaroff DM (2005) Psychosocial factors and interleukin-6 among women with advanced ovarian cancer. Cancer 104:305–313

    Article  PubMed  Google Scholar 

  22. Curtis BM, O’Keefe JH (2002) Autonomic tone as a cardiovascular risk factor: the dangers of chronic fight or flight. Mayo Clin Proc 77:45–54

    Article  PubMed  Google Scholar 

  23. Dakak N, Quyyumi AA, Eisenhofer G, Goldstein DS, Cannon RO (1995) Sympathetically mediated effects of mental stress on the cardiac microcirculation of patients with coronary artery disease. Am J Cardiol 76:125–130

    Article  PubMed  Google Scholar 

  24. Daly J, Sindone AP, Thompson DR, Hancock K, Chang E, Davidson P (2002) Barriers to participation in and adherence to cardiac rehabilitation programs: a critical literature review. Prog Cardiovasc Nurs 17:8–17

    Article  PubMed  Google Scholar 

  25. DiMatteo MR (2004) Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol 23:207–218

    Article  PubMed  Google Scholar 

  26. Eng PM, Rimm EB, Fitmaurice G, Kawachi I (2002) Social ties and change in social ties in relation to subsequent total and cause-specific mortality and coronary heart disease incidence in men. Am J Epidemiol 155:700–709

    Article  PubMed  Google Scholar 

  27. Felton B, Shinn M (1992) Social integration and social support: moving “social support” beyond the individual level. J Community Psychol 20:103–115

    Article  Google Scholar 

  28. Ford ES, Ahluwalia IB, Galuska DA (2000) Social relationships and cardiovascular disease risk factors: findings from the third national health and nutrition examination survey. Prev Med 30:83–92

    Article  PubMed  Google Scholar 

  29. Ford ES, Loucks EB, Berkman L (2006) Social integration and concentrations of C-reactive protein among US adults. Ann Epidemiol 38:835–842

    Google Scholar 

  30. Frasure-Smith N, Prince R (1985) The ischemic heart disease life stress monitoring program: impact on mortality. Psychosom Med 47:431–445

    Article  PubMed  Google Scholar 

  31. Frasure-Smith N, Prince R (1989) Long-term follow-up of the ischemic heart disease life stress monitoring program. Psychosom Med 51:485–513

    Article  PubMed  Google Scholar 

  32. Frasure-Smith N, Lesperance F, Talajic M (1995) The impact of negative emotions on prognosis following myocardial infarction: is it more than depression? Health Psychol 14:388–398

    Article  PubMed  Google Scholar 

  33. Frasure-Smith N, Lespérance F, Prince RH, Verrier P, Garber RA, Juneau M, Wolfson C, Bourassa MG (1997) Randomized trial of home-based psychosocial nursing intervention for patients recovering from myocardial infarction. Lancet 350:473–479

    Article  PubMed  Google Scholar 

  34. Friedman EM, Hayney MS, Love GD, Urry HL, Rosenkranz MA, Davidson RJ, Singer BH, Ryff CD (2005) Social relationships, sleep quality, and interleukin-6 in aging women. PNAS 102:18757–18762

    Article  PubMed  PubMed Central  Google Scholar 

  35. Gafarov VV, Panov DO, Gromova EA, Gagulin IV, Gafarova AV (2013) The influence of social support on risk of acute cardiovascular diseases in female population aged 25–64 in Russia. Int J Circumpolar Health 5:72

    Google Scholar 

  36. Gerin W, Pieper C, Levy R, Pickering TG (1992) Social support in social interaction: a moderator of cardiovascular reactivity. Psychosom Med 54:324–336

    Article  PubMed  Google Scholar 

  37. Gerin W, Milner D, Chawla S, Pickering TG (1995) Social support as a moderator of cardiovascular reactivity in women: a test of the direct effects and buffering hypotheses. Psychosom Med 57:16–22

    Article  PubMed  Google Scholar 

  38. Glass TA, McAtee MJ (2006) Behavioral science at the crossroads in public health: extending horizons, envisioning the future. Soc Sci Med 62:1650–1671

    Article  PubMed  Google Scholar 

  39. Glass TA, Matchar DB, Belyea M, Feussner JR (1993) Impact of social support on outcome in first stroke. Stroke 24:64–70

    Article  PubMed  Google Scholar 

  40. Glass TA, Berkman LF, Hiltunen EF, Furie K, Glymour MM, Fay ME, Ware J (2004) The families in recovery from stroke trial (FIRST): primary study results. Psychosom Med 66:889–897

    Article  PubMed  Google Scholar 

  41. Gorkin L, Schron EB, Brooks MM, Wiklund I, Kellen J, Verter J, Schoenberger JA, Pawitan Y, Morris M, Shumaker S (1993) Psychosocial predictors of mortality in the cardiac arrhythmia suppression Trial-1 (CAST-1). Am J Cardiol 71:263–267

    Article  PubMed  Google Scholar 

  42. Greenspan FS, Baxter JD (1994) Basic and clinical endocrinology. Appleton and Lange, Norwalk

    Google Scholar 

  43. Grewen M, Girdler SS, Amico J, Light KC (2005) Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosom Med 67:531–538

    Article  PubMed  Google Scholar 

  44. Grippo AJ, Lamb DG, Carter CS, Porges SW (2007) Social isolation disrupts autonomic regulation of the heart and influences negative affective behaviors. Biol Psychiatry 62:1162–1170

    Article  PubMed  PubMed Central  Google Scholar 

  45. Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U (2003) Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry 54:1389–1398

    Article  PubMed  Google Scholar 

  46. Hogan BE, Linden W, Najaran B (2002) Social support interventions: do they work? Clin Psychol Rev 22:381–440

    Article  Google Scholar 

  47. Hossack KF, Brown BG, Stewart DK, Dodge HT (1984) Diltiazem-induced blockade of sympathetically mediated constriction of normal and diseased coronary arteries: lack of epicardial coronary dilatory effect in humans. Circulation 70:465–471

    Article  PubMed  Google Scholar 

  48. House JS (2001) Social isolation kills, but how and why? Psychosom Med 63:273–274

    Article  PubMed  Google Scholar 

  49. House JS, Robbins C, Metzner HL (1982) The association of social relationships and activities with mortality: prospective evidence from the Tecumseh community health study. Am J Epidemiol 116:123–140

    Article  PubMed  Google Scholar 

  50. Ikeda A, Iso H, Kawachi I, Yamagishi K, Inoue M, Tsugane S (2008) Stroke 39:768–775

    Article  PubMed  Google Scholar 

  51. Johnson NJ, Backlund E, Sorlie PD, Loveless CA (2000) Marital status and mortality: the National Longitudinal Mortality Study. Ann Epidemiol 10:224–238

    Article  PubMed  Google Scholar 

  52. Kamarck TW, Manuck SB, Jennings JR (1990) Social support reduces cardiovascular reactivity to psychological challenge: a laboratory model. Psychosom Med 52:42–58

    Article  PubMed  Google Scholar 

  53. Kamarck TW, Annunziato B, Amateau LM (1995) Affiliation moderates the effects of social threat on stress-related cardiovascular responses: boundary conditions for a laboratory model of social support. Psychosom Med 57:183–194

    Article  PubMed  Google Scholar 

  54. Kamarck TW, Peterman AH, Raynor DA (1998) The effects of the social environment on stress-related cardiovascular activation: current findings, prospects, and implications. Ann Behav Med 20:247–256

    Article  PubMed  Google Scholar 

  55. Kaplan GA, Salonen JT, Cohen RD (1988) Social connections and mortality from all causes and from cardiovascular disease: prospective evidence from eastern Finland. Am J Epidemiol 128:370–380

    Article  PubMed  Google Scholar 

  56. Kaplan JR, Adams MR, Clarkson TB, Manuck SB, Shively CA, Williams JK (1996) Psychosocial factors, sex differences, and atherosclerosis: lessons from animal models. Psychosom Med 58:598–611

    Article  PubMed  Google Scholar 

  57. Kawachi I, Coldtiz GA, Ascherio A, Rimm EB, Giovannucci E, Stampfer MJ, Willet WC (1996) A prospective study of social networks in relation to total mortality and cardiovascular disease in men in the USA. J Epidemiol Community Health 50:245–251

    Article  PubMed  PubMed Central  Google Scholar 

  58. Kiecolt-Glaser JK, Greenberg B (1984) Social support as a moderator of the aftereffects of stress in female psychiatric inpatients. J Pers Soc Psychol 93:192–199

    Google Scholar 

  59. Knox SS, Czajkowski S (1997) The influence of behavioral and psychosocial factors on cardiovascular health in women. In: Gallant SJ, Keita GP, Royak-Schaler R (eds) Health care for women: psychological, social, and behavioral influences. American Psychological Association, Washington, DC

    Google Scholar 

  60. Knox SS, Uvnas-Moberg K (1998) Social isolation and cardiovascular disease: an atherosclerotic pathway? Psychoneuroendocrinology 23:877–890

    Article  PubMed  Google Scholar 

  61. Knox SS, Adelman A, Ellison C, Arnett DK, Siegmund K, Weidner G, Province MA (2000) Hostility, social support, and carotid artery atherosclerosis in the National Heart, Lung, and Blood Institute family heart study. Am J Cardiol 86:1086–1089

    Article  PubMed  Google Scholar 

  62. Krumholz HM, Butler J, Miller J, Vaccarino V, Williams CS, Mendes de Leon CF, Seeman TE, Kasl SV, Berkman LF (1998) Prognostic importance of emotional support for elderly patients hospitalized with heart failure. Circulation 97:958–964

    Article  PubMed  Google Scholar 

  63. Kulik JA, Mahler HI (1989) Social support and recovery from surgery. Health Psychol 8:221–238

    Article  PubMed  Google Scholar 

  64. Kuper H, Marmot M, Hemmingway H (2002) Systematic review of prospective cohort studies of psychosocial factors in the etiology and prognosis of coronary heart disease. Semin Vasc Med 2:267–314

    Article  PubMed  Google Scholar 

  65. Lepore SJ (1995) Cynicism, social support, and cardiovascular reactivity. Health Psychol 14:210–216

    Article  PubMed  Google Scholar 

  66. Lepore SJ, Allen KA, Evans GW (1993) Social support lowers cardiovascular reactivity to an acute stressor. Psychosom Med 55:518–524

    Article  PubMed  Google Scholar 

  67. Lett HS, Blumenthal JA, Babyak MA, Strauman TJ, Robins C, Sherwood A (2005) Social support and coronary heart disease: epidemiologic evidence and implications for treatment. Psychosom Med 67:869–878

    Article  PubMed  Google Scholar 

  68. Libby P (2002) Inflammation in atherosclerosis. Nature 420:868–874

    Article  PubMed  Google Scholar 

  69. Lochner KA, Kawachi I, Brennan RT, Buka SA (2003) Social capital and neighborhood mortality rates in Chicago. Soc Sci Med 56:1797–1805

    Article  PubMed  Google Scholar 

  70. Loucks EB, Sullivan L, D’agostino RB, Larson MG, Berkman LF, Benjamin EJ (2006) Social networks and inflammatory markers in the Framingham heart study. J Biosoc Sci 38:835–842

    Article  PubMed  Google Scholar 

  71. Lund R, Christensen U, Nilsson CJ, Kriegbaum M, Hulvej Rod N (2014) Stressful social relations and mortality: a prospective cohort study. J Epidemiol Community Health 68:720–727

    Article  PubMed  Google Scholar 

  72. Lutgendorf SK, Anderson B, Sorosky JL, Buller RE, Lubaroff DM (2000) Interleukin-6 and use of social support in gynecologic cancer patients. Int J Behav Med 7:127–142

    Article  Google Scholar 

  73. Luttik ML, Jaarsma T, Moser D, Sanderman R, van Veldhuisen DJ (2005) The importance and impact of social support on outcomes in patients with heart failure: an overview of the literature. J Cardiovasc Nurs 20:162–169

    Article  PubMed  Google Scholar 

  74. Milagros RC, King J, Ma Y, Reed GW (2004) Stress, social support, and cortisol: inverse associations? Behav Med 30:11–21

    Article  Google Scholar 

  75. Mitchell PH, Powell L, Blumenthal J, Norten J, Ironson G, Pitula CR, Froelicher ES, Czajkowski S, Youngblood M, Huber M, Berkman LF (2003) A short social support measure for patients recovering from myocardial infarction: the ENRICHD social support inventory. J Cardpulm Rehabil 23:398–403

    Article  Google Scholar 

  76. Molloy GJ, Perkins-Porras L, Bhattacharyya MR, Strike PC, Steptoe A (2008) Practical support predicts medication adherence and attendance at cardiac rehabilitation following acute coronary syndrome. J Psychosom Res 65:581–586

    Article  PubMed  Google Scholar 

  77. Mookadam F, Arthur H (2004) Social support and its relationship to morbidity and mortality after acute myocardial infarction. Arch Intern Med 164:1514–1518

    Article  PubMed  Google Scholar 

  78. Nieminen T, Härkänen T, Martelin T, Borodulin K, Koskinen S (2015) Social capital and all-cause mortality among Finnish men and women aged 30–79. Eur J Pub Health 25:972–978

    Article  Google Scholar 

  79. Ong AD, Allaire JC (2005) Cardiovascular intraindividual variability in later life: the influence of social connectedness and positive emotions. Psychol Aging 20:476–485

    Article  PubMed  Google Scholar 

  80. Orth-Gomer K, Johnson JV (1987) Social network interaction and mortality. J Chronic Dis 40:949–957

    Article  PubMed  Google Scholar 

  81. Orth-Gomer K, Rosengren A, Wilhelmsen L (1993) Lack of social support incidence of coronary heart disease in middle-aged Swedish men. Psychosom Med 55:37–43

    Article  PubMed  Google Scholar 

  82. Orth-Gomer K, Horsten M, Schenck-Gustafson K et al (1998) Social relations and extent and severity of coronary artery disease. Eur Heart J 19:1648–1656

    Article  PubMed  Google Scholar 

  83. Oxman TE, Freeman DH, Manheimer ED (1995) Lack of social participation or religious strength and comfort as risk factors for death after cardiac surgery in the elderly. Psychosom Med 57:5–15

    Article  PubMed  Google Scholar 

  84. Reed D, McGee D, Yano K, Feinlab M (1983) Social networks and coronary heart disease among Japanese men in Hawaii. Am J Epidemiol 117:384–396

    Article  PubMed  Google Scholar 

  85. Reifman A (1995) Social relationships, recovery from illness, and survival: a literature review. Ann Behav Med 17:124–131

    Article  PubMed  Google Scholar 

  86. Rosengren A, Willhelmsen L, Orth-Gomér K (2004) Coronary disease in relation to social support and social class in Swedish men: a 15 year follow-up in the study of men born in 1933. Eur Heart J 25:56–63

    Article  PubMed  Google Scholar 

  87. Rosenwinkel ET, Bloomfield DM, Arwady MA, Goldsmith RL (2001) Exercise and autonomic function in health and cardiovascular disease. Cardiol Clin 19:39–387

    Article  Google Scholar 

  88. Ruberman W, Weinblatt E, Goldberg JD, Chaudhary BS (1984) Psychosocial influences on mortality after myocardial infarction. N Engl J Med 311:552–559

    Article  PubMed  Google Scholar 

  89. Rutledge T, Reis SE, Olaon M, Owens J, Kelsey SF, Pepine CJ, Mankad S, Rogers WJ, Bairey Merz CN, Sopko G, Cornell CE, Sharaf B, Matthews KA (2004) Social networks are associated with lower mortality rates among women with suspected coronary disease: the National Heart, Lung, and Blood Institute-sponsored Women’s ischemia syndrome evaluation study. Psychosom Med 66:882–888

    Article  PubMed  Google Scholar 

  90. Rutledge T, Linke SE, Olson MB, Francis J, Johnson D, Bittner V, York K, McClure C, Kelsey SF, Reis SE, Cornell CE, Vaccarino V, Sheps DS, Shaw LJ, Krantz DS, Parashar S, Bairey Merz CN (2008) Social networks and incident stroke among women with suspected myocardial ischemia. Psychosom Med 70:282–287

    Article  PubMed  Google Scholar 

  91. Sarason BR, Sarason IG (1994) Assessment of social support. In: Shumaker SA, Czajkowski SM (eds) Social support and cardiovascular disease. Plenum Press, New York

    Google Scholar 

  92. Scheffler RM, Brown TT, Syme L, Kawachi I, Tolstyk I, Iribarren C (2007) Community-level social capital and recurrence of acute coronary syndrome. Soc Sci Med 66:1603–1613

    Article  Google Scholar 

  93. Schoenbach V, Kaplan BH, Freedman L (1986) Social ties and mortality in Evan County, Georgia. Am J Epidemiol 123:577–691

    Article  PubMed  Google Scholar 

  94. Seeman TE (1996) Social ties and health: the benefits of social integration. Ann Epidemiol 6:442–451

    Article  PubMed  Google Scholar 

  95. Seeman TE, Syme L (1987) Social networks and coronary artery disease: a comparison of the structure and function of social relations as predictors of disease. Psychosom Med 49:341–354

    Article  PubMed  Google Scholar 

  96. Shively CA, Clarkson TB, Kaplan JR (1989) Social deprivation and coronary artery atherosclerosis in female cynomolgus monkeys. Atherosclerosis 77:69–76

    Article  PubMed  Google Scholar 

  97. Smith TW, Ruiz JM (2002) Psychosocial influences on the development and course of coronary heart disease: current status and implications for research and practice. J Consult Clin Psychol 70:548–568

    Article  PubMed  Google Scholar 

  98. Stringhini S, Berkman L, Dugravot A, Ferrie JE, Marmot M, Kivimaki M, Singh-Manoux A (2012) Socioeconomic status, structural and functional measures of social support, and mortality: the British Whitehall II cohort study, 1985–2009. Am J Epidemiol 175:1275–1283

    Article  PubMed  PubMed Central  Google Scholar 

  99. Sundquist J, Johannson S, Yang M, Sundquist K (2006) Low linking social capital as a predictor of coronary heart disease in Sweden: a cohort study of 2.8 million people. Soc Sci Med 62:954–963

    Article  PubMed  Google Scholar 

  100. Taylor SE, Klein LC, Lewis BP, Gruenewald TL, Gurung RAR, Updegraff JA (2000) Biobehavioral responses to stress in females: tend-and-befriend, not fight-or-flight. Psychol Rev 107:411–429

    Article  PubMed  Google Scholar 

  101. The ENRICHD Investigators (2000) Enhancing recovery in coronary heart disease patients (ENRICHD): study design and methods. Am Heart J 139:1–9

    Article  Google Scholar 

  102. Turner-Cobb JM, Sephton SE, Koopman C, Blake-Mortimer J, Spiegel D (2000) Social support and salivary cortisol in women with metastatic breast cancer. Psychosom Med 62:337–345

    Article  PubMed  Google Scholar 

  103. Uchino BN (2004) Social support and physical health. Yale University Press, New Haven

    Book  Google Scholar 

  104. Uchino BN (2006) Social support and health: a review of physiological processes potentially underlying links to disease outcomes. J Behav Med 29:377–387

    Article  PubMed  Google Scholar 

  105. Uchino BN, Cacioppio JT, Markaley W, Glaser R, Keicolt-Glaser J (1995) Appraisal support predicts age-related differences in cardiovascular function in women. Health Psychol 14:556–562

    Article  PubMed  Google Scholar 

  106. Uchino BN, Cacioppo JT, Kiecolt-Glaser JK (1996) The relationship between social support and physiological processes: a review with emphasis on underlying mechanisms and implications for health. Psychol Bull 119:488–531

    Article  PubMed  Google Scholar 

  107. Uchino BN, Holt-Lunstad J, Uno D, Betancourt R, Garvey TS (1999) Social support and age-related differences in cardiovascular function: an examination of potential mediators. Ann Behav Med 21:135–142

    Article  PubMed  Google Scholar 

  108. Uvnas-Moberg K (1998) Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology 23:819–835

    Article  PubMed  Google Scholar 

  109. Van Poppel F, Joung I (2001) Long-term trends in marital status mortality differences in the Netherlands 1850-1970. J Biosoc Sci 33:279–303

    Article  PubMed  Google Scholar 

  110. Wang HX, Mittleman MA, Leineweber C, Orth-Gomer K (2006) Depressive symptoms, social isolation and progression of coronary artery atherosclerosis: the Stockholm female coronary angiography study. Psychother Psychosom 75:96–102

    Article  PubMed  Google Scholar 

  111. Watson SL, Shively CA, Kaplan JR, Line SW (1998) Effects of chronic social separation on cardiovascular disease risk factors in female cynomolgus monkeys. Atherosclerosis 137:259–266

    Article  PubMed  Google Scholar 

  112. Williams CA, Beresford SAA, James SA, LaCroix AZ, Strogatz DS, Wagner EH, Kleinbaum DG, Cutchin LM, Ibrahim MA (1985) The Edgecombe County high blood pressure control program: III. Social support, social stressors, and treatment dropout. Am J Public Health 75:483–486

    Article  PubMed  PubMed Central  Google Scholar 

  113. Williams RB, Barefoot JC, Califf RM, Haney TL, Saunders WB, Pryor DB, Hlatky MA, Siegler IC, Mark DB (1992) Prognostic importance of social and economic resources among medically treated patients with angiographically documented coronary artery disease. JAMA 267:520–524

    Article  PubMed  Google Scholar 

  114. Writing Committee for the ENRICHD Investigators (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial. JAMA 289:3106–3116

    Article  Google Scholar 

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Czajkowski, S.M., Arteaga, S.S., Burg, M.M. (2022). Social Support and Cardiovascular Disease. In: Waldstein, S.R., Kop, W.J., Suarez, E.C., Lovallo, W.R., Katzel, L.I. (eds) Handbook of Cardiovascular Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-85960-6_25

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