Encyclopedia of Clinical Neuropsychology

2011 Edition
| Editors: Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan

Guillain–Barré Syndrome

  • Fary Khan
  • N. G. Louisa
Reference work entry
DOI: https://doi.org/10.1007/978-0-387-79948-3_554


Short Description or Definition

Guillain–Barré Syndrome (GBS) is a monophasic illness of immune etiology that presents as an evolving sensorimotor polyneuropathy of varying severity as a result of an inflammation of the peripheral nerves and nerve roots. GBS is a major cause of acute ascending neuromuscular paralysis and is often associated with autonomic dysfunction.


GBS is recognized as a heterogeneous syndrome with several variant forms (see Table 1). The commonest type of GBS is AIDP. Axonal subtypes include acute motor axonal neuropathy and acute motor and sensory axonal neuropathy. Variants include Miller Fisher syndrome (cranial nerve involvement, ataxia) and acute pan-dysautonomia.
Guillain–Barré Syndrome. Table 1

Frequency of features...

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Fary Khan
    • 1
  • N. G. Louisa
    • 2
  1. 1.Department of MedicineUniversity of Melbourne and the Royal Melbourne HospitalParkville, VAAustralia
  2. 2.Department of Rehabilitation MedicineRoyal Melbourne HospitalParkvilleAustralia