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Dementia with Lewy Bodies

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Encyclopedia of Clinical Neuropsychology
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Synonyms

Cortical lewy body disease (CLBD); Diffuse lewy body disease (DLBD); Lewy body dementia (LBD); Senile dementia of lewy type

Definition

Dementia with Lewy bodies (DLB) is a degenerative disorder characterized by progressive cognitive decline combined with three additional defining features: (1) pronounced fluctuations in alertness and attention (e.g., frequent drowsiness, lethargy, and disorganized speech), (2) visual hallucinations, and (3) parkinsonian motor symptoms (e.g., resting tremor, muscle rigidity, bradykinesia, and/or postural instability) (McKeith et al., 1996). The most recent consensus criteria have been modified to include additional features that may be suggestive of possible DLB (McKeith et al., 2005) (See Table 1).

Dementia with Lewy Bodies. Table 1 Revised criteria for the clinical diagnosis of probable or possible DLB (Adapted from McKeith et al., 2005)

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References and Readings

  • Goldmann Gross, R., Siderowf, A., & Hurtig, H. I. (2008). Cognitive impairment in Parkinson’s disease and dementia with lewy bodies: A spectrum of disease. Neurosignals, 16(1), 24–34.

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  • McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H. et al. (2005). Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology, 65(12), 1863–1872.

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  • McKeith, I. G., Galasko, D., Kosaka, K., Perry, E. K., Dickson, D. W., Hansen, L. A. et al. (1996). Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology, 47(5), 1113–1124.

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  • McKeith, I. G., Perry, E. K., & Perry, R. H. (1999). Report of the second dementia with Lewy body international workshop: diagnosis and treatment. Consortium on Dementia with Lewy Bodies. Neurology, 53(5), 902–905.

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Kraybill, M., Suchy, Y. (2011). Dementia with Lewy Bodies. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-79948-3_502

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  • DOI: https://doi.org/10.1007/978-0-387-79948-3_502

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