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Ablation is the removal or destruction of an anatomical structure by means of surgery, disease, or other physical or energetic process. Ablation is employed as a treatment of various medical conditions and includes recent advances in technology. Surgical ablation of neuronal pathways to the globus pallidus or thalamus has been used historically to treat parkinsonism. Interventional pain experts use radiofrequency ablation of nerves in the spine to treat chronic back pain. Gamma radiation or “gamma knife surgery” is used to excise brain tumors when traditional surgical ablation is too destructive to neighboring tissues. Even with sophisticated neurosurgical techniques, ablation of any type in the nervous system may still produce unwanted motor, sensory, or cognitive-behavioral impairments.
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References and Readings
Krayenbuhl, H., Wyss, O. A., & Yasargil, M. G. (1961). Bilateral thalamotomy and pallidotomy as treatment for bilateral parkinsonism. Journal of Neurosurgery, 18, 429–444.
Lord, S. M., & Bogduk, N. (2002). Radiofrequency procedures in chronic pain. Best Practice & Research. Clinical Anaesthesiology, 16, 597–617.
Lunsford, L. D., Flickinger, J. C., & Steiner, L. (1988). The gamma knife. JAMA, 259, 2544.
Shah, R. V., Ericksen, J. J., & Lacerte, M. (2003). Interventions in chronic pain management. 2. New frontiers: Invasive nonsurgical interventions. Archives Physical Medicine and Rehabilitation, 84, S39–44.
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Wong, E. (2011). Ablation. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-79948-3_3
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DOI: https://doi.org/10.1007/978-0-387-79948-3_3
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