Generic Name
Ziprasidone
Brand Name
Geodon
Class
Atypical Neuroleptic
Proposed Mechanism(s) of Action
Blocks dopamine-2 receptors, blocks serotonin 2A receptors thus increasing presynaptic related catecholamine release.
Indication
Schizophrenia, delaying relapse in schizophrenia, acute agitation in schizophrenia, and acute mania.
Off Label Use
Psychotic disorders, bipolar maintenance, bipolar depression, behavioral disturbances associated with dementia and in children and adolescents, and impulse control disorders.
Side Effects
Serious
Seizures, neuroleptic malignant syndrome.
Common
Dizziness, extrapyramidal symptoms, sedation, nausea, dry mouth, skin rash, tardive dyskinesia, orthostatic hypotension, and activation effects.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences and Readings
Physicians’ Desk Reference (62nd ed.). (2007). Montvale, NJ: Thomson PDR.
Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York, NY: Cambridge University Press.
Additional Information
Drug Interaction Effects: http://www.drugs.com/drug_interactions.html
Drug Molecule Images: http://www.worldofmolecules.com/drugs/
Free Drug Online and PDA Software: www.epocrates.com
Gene-Based Estimate of Drug interactions: http://mhc.daytondcs.com: 8080/cgi bin/ddiD4?ver=4&task=getDrugList
Pill Identification: http://www.drugs.com/pill_identification.html
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this entry
Cite this entry
Courtney, J.C., Akins, C. (2011). Ziprasidone. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-79948-3_1725
Download citation
DOI: https://doi.org/10.1007/978-0-387-79948-3_1725
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-79947-6
Online ISBN: 978-0-387-79948-3
eBook Packages: Behavioral Science