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Dextroamphetamine (Dexedrine, Dextrostat)

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Synonyms

Adderall/Adderall XR (mixture with other amphetamines); Dex; Dexamyl (mixture with amobarbital); Dextroamphetamine; Dextrostat; Scop-Dex (mixture with scopolamine); Speed; Vyvanse (prodrug of dextroamphetamine)

Definition

A psychostimulant utilized in the treatment of attention deficit-hyperactivity disorder (ADHD), chemically derived from amphetamine, which has been shown to reduce hyperkinetic or hyperactive behavior, and affect motor activity, vigilance, learning, and mood. Similar to Ritalin, Cylert, and other amphetamines, Dexedrine is a highly-controlled drug under various drug control laws (U.S. Schedule II, UK Class B, etc.).

Description

Introduced in 1937 by Smith, Kline, and French (SK&F), Dexedrine found wide acceptance among physicians in the treatment of ADHD (then diagnosed as “minimal brain dysfunction”), narcolepsy, depression, and obesity. A 1950 study of Dexedrine use [1] in children found that 50–60% of the drug’s users had become more subdued and 20%...

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Dextroamphetamine (Dexedrine, Dextrostat). Fig. 1

References

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  3. Comments of Dr. George Bray. (1992). Weight-loss pills: Do they really work? Larry KingLive: Cable News Network.

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  4. Dexedrine a pain-killer for dying cancer victims. United Press International wireservice: 8 June 1982.

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  5. Food and Drug Administration courtesy GlaxoSmithKline, online at http://www.gsksource.com/gskprm/htdocs/documents/DEXEDRINE-PI-MG.PDF

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Balogh, N.J. (2011). Dextroamphetamine (Dexedrine, Dextrostat). In: Goldstein, S., Naglieri, J.A. (eds) Encyclopedia of Child Behavior and Development. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79061-9_840

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