Encyclopedia of Complexity and Systems Science

2009 Edition
| Editors: Robert A. Meyers (Editor-in-Chief)

DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires

  • Baoquan Ding
  • Yan Liu
  • Sherri Rinker
  • Hao Yan
Reference work entry
DOI: https://doi.org/10.1007/978-0-387-30440-3_132

Definition of the Subject

DNA self‐assembly is a very useful and powerful tool for bottom-upnanofabrication . It consists of combining unusual DNA motifs by specific structurallywell‐defined cohesive interactions (sticky ends) to produce target materials with predictable 3D structure. This method hasgenerated versatile DNA nanostructures including polyhedral catenanes, robust nanomechanical devices, and a variety of periodic and aperiodic arraysin two dimensions. DNA self‐assembled structures have been used as the template for different guest functional molecules such as proteins, metallicnano‐particles, DNA based nano‐devices and highly conductive nanowires. Regular lattices made of DNA could hold copies of large biologicalmolecules in a highly ordered array for x-ray crystallography to determine their structure, an important step in the “rational” design ofdrugs. Alternatively, the lattices could serve as scaffolding for nanoelectronic components, either as a working device or as...

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Baoquan Ding
    • 1
  • Yan Liu
    • 2
  • Sherri Rinker
    • 2
  • Hao Yan
    • 2
  1. 1.Molecular FoundryLawrence Berkeley National LabBerkeleyUSA
  2. 2.Department of Chemistry and Biochemistry and Biodesign InstituteArizona State UniversityTempeUSA