Skip to main content

Abstract:

This chapter summarizes the literature on assessment, maintenance, treatment, and mechanisms of change in treatment of patients with panic disorder with or without agoraphobia. Relevant theoretical contributions which are discussed may help to understand the genesis and maintenance factors of panic disorder and agoraphobia. Further, we provide an overview of empirically supported treatment approaches for these disorders and discuss the mechanisms of change involved in these treatments Knowledge of the burgeoning literature in this area is relevant for the development of basic and expert clinical competencies in panic disorder/agoraphobia. It is argued that the clinician should first be familiar with the diagnostic criteria for panic disorder and for agoraphobia. Knowledge of structured clinical interviews is needed to be able to formalize the diagnosis. In addition, knowledge of self-report measures, behavioral assessment, and self-monitoring is needed to assess the quality and severity of panic disorder and agoraphobia and to evaluate progress of treatment. Further, basic competencies also require knowledge on which factors are involved in the maintenance of these disorders. In addition, basic clinical competencies should entail knowledge about psycho-education, and evidence-based protocols for conducting interoceptive exposure and exposure in vivo outside the therapist office. Expert clinical competencies may entail advanced understanding and skills of applying psychological and pharmacological procedures to augment exposure therapy, skills in enactment of cognitive therapy and couple therapy, knowledge and skills to deal with panic disorder and agoraphobia in cases with comorbid disorders (e.g. substance abuse/dependence, and depression) as well sensitivity to anxiety related cultural factors.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 949.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 549.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.

    Google Scholar 

  • Antony, M. M., Ledley, D. R., Liss, A., & Swinson, R. P. (2006). Responses to symptom induction exercises in panic disorder. Behaviour Research and Therapy, 44, 85–98.

    Article  PubMed  Google Scholar 

  • Arntz, A., & van den Hout, M. (1996). Psychological treatment of panic disorder without agoraphobia: Cognitive therapy versus applied relaxation. Behaviour Research and Therapy, 34, 113–121.

    Article  PubMed  Google Scholar 

  • Bakker, A., van Balkom, A. J. L. M., Spinhoven, P., Blaauw, B. M. W. J., & van Dyck, R. (1998). Follow-up on the treatment of panic disorder with or without agoraphobia: A Quantitative review. Journal of Nervous and Mental Disease, 186, 414–419.

    Article  PubMed  Google Scholar 

  • Ballenger, J. C., Davidson, J. R., Lecrubier, Y., Nutt, D. J., Baldwin, D. S., den Boer, J. A., et al. (1998). Consensus statement on panic disorder from the International Consensus Group on Depression and Anxiety. Journal of Clinical Psychiatry, 59(Suppl 8), 47–54.

    PubMed  Google Scholar 

  • Barlow, D. H. (1988). Anxiety and its disorders. New York: Guilford.

    Google Scholar 

  • Barlow, D. H. (2008). Clinical handbook of psychological disorders: A step-by-step treatment manual (4th ed.). New York: Guilford.

    Google Scholar 

  • Barlow, D. H., & Craske, M. G. (2007). Mastery of your anxiety and panic (4th ed.). New York: Oxford University Press.

    Google Scholar 

  • Barlow, D. H., Craske, M., Cerny, J., & Klosko, J. (1989). Behavioral treatment of panic disorder. Behavior Therapy, 20, 261–282.

    Article  Google Scholar 

  • Barlow, D. H., Gorman, J. M., Shear, M. K., & Woods, S. W. (2000). Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial. Journal of the American Medical Associatio, 283(19), 2529–2536.

    Article  Google Scholar 

  • Baum, M. (1988). Spontaneous recovery from the effects of flooding (exposure) in animals. Behaviour Research and Therapy, 26, 185–186.

    Article  PubMed  Google Scholar 

  • Beck, A. T., Emery, G., & Greenberg, R. (1985). Anxiety disorders and phobias: A cognitive perspective. New York: Basic Books.

    Google Scholar 

  • Beck, A. T., Sokol, L., Clark, D. A., Berschick, R., & Wright, F. (1992). A cross-over study of focused cognitive therapy for panic disorder. American Journal of Psychiatry, 149, 778–783.

    PubMed  Google Scholar 

  • Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.

    Article  PubMed  Google Scholar 

  • Beck, J., Stanley, M. A., Baldwin, L. E., Deagle, E. A., & Averill, P. M. (1994). Comparison of cognitive therapy and relaxation training for panic disorder. Journal of Consulting and Clinical Psychology, 62, 818–826.

    Article  PubMed  Google Scholar 

  • Bekker, M. H. J., & van Mens-Verhulst, J. (2007). Anxiety disorders: Sex differences in prevalence, degree, and background, but gender-neutral treatment. Journal of Gender Medicine, 4(Suppl.), S178–S193.

    Article  Google Scholar 

  • Bouchard, S., Gauthier, J., Laberge, B., French, D., Pelletier, M., & Godbout, D. (1996). Exposure versus cognitive restructuring in the treatment of panic disorder with agoraphobia. Behaviour Research and Therapy, 34, 213–224.

    Article  PubMed  Google Scholar 

  • Bouchard, S., Pelletier, M.-H., Gauthier, J., Cote, G., & Laberge, B. (1997). The assessment of panic using self-report: A comprehensive survey of validated instruments. Journal of Anxiety Disorders, 11, 89–111.

    Article  PubMed  Google Scholar 

  • Bouton, M. E. (1993). Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychological Bulletin, 114(1), 80–99.

    Article  PubMed  Google Scholar 

  • Bouton, M. E., Mineka, S., & Barlow, D. H. (2001). A modern learning theory perspective on the etiology of panic disorder. Psychological Review, 108(1), 4–32.

    Article  PubMed  Google Scholar 

  • Bouton, M. E., Woods, A. M., & Pineno, O. (2004). Occasional reinforced trials during extinction can slow the rate of rapid reacquisition. Learning and Motivation, 35, 371–390.

    Article  Google Scholar 

  • Bowen, R. C., D’Arcy, C., Keegan, D., & Van Senthilsel, A. (2000). A controlled trial of cognitive behavioral treatment of panic in alcoholic inpatients with comorbid panic disorder. Addictive Behavior, 4, 593–597.

    Article  Google Scholar 

  • Brown, T. A., DiNardo, P. A., & Barlow, D. H. (1994). Anxiety disorders interview schedule for DSM-IV. Graywind Publications, Albany, NY.

    Google Scholar 

  • Brown, T., DiNardo, P., & Barlow, D. (2004). Anxiety disorders interview schedule adult version (ADIS-IV): Client interview schedule. Boston, MA: Graywind.

    Google Scholar 

  • Brown, T. A., Di Nardo, P. A., Lehman, C. L., & Campbell, L. A. (2001). Reliability of DSM-IV anxiety and mood disorders: Implications for the classification of emotional disorders. Journal of Abnormal Psychology, 110(1), 49–58.

    Article  PubMed  Google Scholar 

  • Bruce, T. J., Spiegel, D. A., Gregg, S. F., & Nuzzarello, A. (1995). Predictors of alprazolam discontinuation with and without cognitive behavior therapy in panic disorder. American Journal of Psychiatry, 152(8), 1156––1160.

    PubMed  Google Scholar 

  • Burke, M., Drummond, L. M., & Johnston, D. W. (1997). Treatment choice for agoraphobic women: exposure of cognitive-behaviour therapy? British Journal of Clinical Psychology, 36, pp. 409–420.

    Article  PubMed  Google Scholar 

  • Cain, C. K., Blouin, A. M., & Barad, M. (2004). Adrenergic transmission facilitates extinction of conditional fear in mice. Learning & Memory, 11(2), 179–187.

    Article  Google Scholar 

  • Carlbring, P., Bohman, S., Brunt, S., Buhrman, M., Westling, B. E., Ekselius, L., et al. (2006). Remote treatment of panic disorder: A randomized trial of internet-based cognitive behavior therapy supplemented with telephone calls. American Journal of Psychiatry, 163, 2119–2125.

    Article  PubMed  Google Scholar 

  • Cerny, J. A., Barlow, D., Craske, M. G., & Himadi, W. G. (1987). Couples treatment of agoraphobia: A two-year follow-up. Behavior Therapy, 18, 401–415.

    Article  Google Scholar 

  • Chambless, D. L. (1982). Characteristics of agoraphobics. In Chambless, D. L., & Goldstein, A. J. (Eds.), Agoraphobia: Multiple perspectives on theory and treatment. New York: Wiley.

    Google Scholar 

  • Chambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984). Assessment of fear of fear in agoraphobics: The body sensations questionnaire and the agoraphobic cognitions questionnaire. Journal of Consulting and Clinical Psychology, 52, 1090–1097.

    Article  PubMed  Google Scholar 

  • Chambless, D. L., Caputo, G. C., Jasin, S. E., Gracely, E. J., & Williams, C. (1985). The Mobility Inventory for Agoraphobia. Behaviour Research & Therapy, 23, 35–44.

    Article  Google Scholar 

  • Chelonis, J. J., Calton, J. L., Hart, J. A., & Schachtman, T. R. (1999). Attenuation of the Renewal Effect by Extinction in Multiple Contexts. Learning and Motivation, 30(1), 1–14.

    Article  Google Scholar 

  • Clark, D. M. (1986). A cognitive approach to panic. Behaviour Research and Therapy, 24, 461–470.

    Article  PubMed  Google Scholar 

  • Clark, D. M., Salkovskis, P. M., & Chalkley, A. J. (1985). Respiratory control as a treatment for panic attacks. Journal of Behavior Therapy and Experimental Psychiatry, 16, 23–30.

    Article  PubMed  Google Scholar 

  • Clark, D. M., Salkovskis, P. M., Hackman, A., Middleton, H., Anastasiades, P., & Gelder, M. (1994). A comparison of cognitive therapy, applied relaxation and imipramine in the treatment of panic disorder. British Journal of Psychiatry, 164, 759–769.

    Article  PubMed  Google Scholar 

  • Clum, G. A. (1990). Coping with panic. Pacific Grove, CA: Brooks/Cole.

    Google Scholar 

  • Cobb, J. P., Mathews, A. A., Childs-Clarke, A., & Blowers, C. M. (1984). The spouse as co-therapist in the treatment of agoraphobia. British Journal of Psychiatry, 144, 282–287.

    Article  PubMed  Google Scholar 

  • Cote, G., Gauthier, J. G., Laberge, B., & Cormier, H. J. (1994). Reduced therapist contact in the cognitive behavioral treatment of panic disorder. Behavior Therapy, 25, 123–145.

    Article  Google Scholar 

  • Cox, B. J. (1996). The nature and assessment of catastrophic thoughts in panic disorder. Behaviour Research and Therapy, 34, 363–374.

    Article  PubMed  Google Scholar 

  • Craske, M. G. (1999). Anxiety disorders. Psychological approaches to theory and treatment. Boulder, CO: Westview.

    Google Scholar 

  • Craske, M. G., & Barlow, D. H. (2008). Panic disorder and agoraphobia. In Barlow, D. H. (Ed.), Clinical handbook of emotional disorders (4th ed., pp 1–52). New York: Guilford Press.

    Google Scholar 

  • Craske, M. G., Brown, T. A., & Barlow, D. H. (1991). Behavioral treatment of panic disorder: A two-year follow-up. Behavior Therapy, 22, 289–304.

    Article  Google Scholar 

  • Craske, M. G., Hermans, D., & Vansteenwegen, D. (2006). Fear and learning. Washington DC: American Psychological Association.

    Google Scholar 

  • Craske, M. G., Kircanski, K., Zelikowsky, M., Mystkowski, J., Chowdhury, N., & Baker, A. (2008). Optimizing inhibitory learning during exposure therapy. Behaviour Research and Therapy, 46(1), 5–27.

    Article  PubMed  Google Scholar 

  • Craske, M. G., Maidenberg, E., & Bystritsky, A. (1995). Brief cognitive-behavioral versus nondirective therapy for panic disorder. Journal of Behavior Therapy and Experimental Psychiatry, 26, 113–120.

    Article  PubMed  Google Scholar 

  • Craske, M. G., Poulton, R., Tsao, J. C. I., & Plotkin, D. (2001). Paths to panic disorder/agoraphobia: An exploratory analysis from age 3 to 21 in an unselected cohort. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 556–563.

    Article  PubMed  Google Scholar 

  • Craske, M. G., Rowe, M., Lewin, M., & Noriega-Dimitri, R. (1997). Interoceptive exposure versus breathing retraining within cognitive-behavioral therapy for panic disorder with agoraphobia. Journal of Clinical Psychology, 36, 85–99.

    Google Scholar 

  • Craske, M. G., & Waters, M. A. (2005). Panic disorder, phobias, and generalized anxiety disorder. Annual Review of Clinical Psychology, 1, 197–226.

    Article  PubMed  Google Scholar 

  • Davey, G. C. L. (1987). An integration of human and animal models of Pavlovian conditioning Associations, cognitions, and attributions. In Davey, G. (Ed.), Cognitive processes and Pavlovian conditioning in humans. (Vol. 83–114). Chichester, UK: Wiley.

    Google Scholar 

  • Davey, G. C. L. (1997). A conditioning model of phobias. In Davey, G. C. L. (Ed.), Phobias: A handbook of theory, research and assessment. Chichester, UK: Wiley.

    Google Scholar 

  • Davis, M., Ressler, K., Rothbaum, B. O., & Richardson, R. (2006). Effects of D-cycloserine on extinction: Translation from preclinical to clinical work. Biological Psychiatry, 60(4), 369–375.

    Article  PubMed  Google Scholar 

  • De Beurs, E., Lange, A., van Dyck, R., Blonk, R. W. B., & Koele, P. (1991). Behavioral assessment of behavioral avoidance in agoraphobia. Journal of Psychopathology and Behavioral Assessment, 13, 285–300.

    Article  Google Scholar 

  • Dreessen, L., & Arntz, A. (1998). The impact of personality disorders on treatment outcome of anxiety disorders: Best-evidence synthesis. Behaviour Research and Therapy, 36(5), 483–504.

    Article  PubMed  Google Scholar 

  • Dreessen, L., Arntz, A., Luttels, C., & Sallaerts, S. (1994). Personality disorders do not influence the results of cognitive behavior therapies for anxiety disorders. Comprehensive Psychiatry, 35(4), 265–274.

    Article  PubMed  Google Scholar 

  • Eelen, P., Hermans, D., & Baeyens, F. (2001). Learning perspectives on anxiety disorders. In Griez, E. J. L., Faravelli, C., Nutt, & D. J., Zohar, J. (Eds.), Anxiety disorders: An introduction to clinical management and research. New York: Wiley.

    Google Scholar 

  • Ehlers, A., & Margraf, J. (1989). The psychophysiological model of panic attacks. In Emmelkamp, P. M. G., Everaerd, W., Kraaimaat, F., & van Son, M. (Eds.), Fresh perspectives on anxiety (pp. 1–29). Amsterdam: Swets.

    Google Scholar 

  • Emmelkamp, P. M. G. (1994). Behavior therapy with adults. In Bergin, A., & Garfield, S. (Eds.), Handbook of psychotherapy and behavior change. New York: Wiley.

    Google Scholar 

  • Emmelkamp, P. M. G. (2004). Behavior therapy with adults. In Lambert, M., Bergin, A., & Garfield, S. (Eds.), Handbook of psychotherapy and behavior change (5th ed.). New York: Wiley.

    Google Scholar 

  • Emmelkamp, P. M. G. (2005). Technological innovations in clinical assessment and psychotherapy. Psychotherapy & Psychosomatics, 74, 336–343.

    Article  Google Scholar 

  • Emmelkamp, P. M. G., Bouman, T. K., & Scholing, A. (1993). Anxiety disorders. Chichester, UK: Wiley.

    Google Scholar 

  • Emmelkamp, P. M. G., Brilman, E., Kuiper, H., & Mersch, P. P. (1986). The treatment of agoraphobia: A comparison of self-instructional training, rational emotive therapy and exposure in vivo. Behavior Modification, 10, 37–53.

    Article  PubMed  Google Scholar 

  • Emmelkamp, P. M. G., & Gerlsma, C. (1994). Marital functioning and the anxiety disorders. Behavior Therapy, 25, 407–429.

    Article  Google Scholar 

  • Emmelkamp, P. M. G., & Kamphuis, J. H. (2007). Personality disorders. New York: Psychology Press/Taylor & Francis.

    Google Scholar 

  • Emmelkamp, P. M. G., Kuipers, A., & Eggeraat, J. (1978). Cognitive modification versus prolonged exposure in vivo: A comparison with agoraphobics. Behaviour Research and Therapy, 16, 33–41.

    Article  PubMed  Google Scholar 

  • Emmelkamp, P. M. G., & Mersch, P. P. (1982). Cognition and exposure in vivo in the treatment of agoraphobia: Short-term and delayed effects. Cognitive Therapy and Research, 6, 77–90.

    Article  Google Scholar 

  • Emmelkamp, P. M. G., & Powers, M. B. (2009). Neo-Kraepelinian diagnosis: Adequacy for phobias and panic. In McKay, D., Abramowitz, J. S., Taylor, S., & Asmundson, G. J. G. (Eds.), Current perspectives on the anxiety disorders: Implications for DSM-V and beyond. New York: Springer (in press).

    Google Scholar 

  • Emmelkamp, P. M. G., Van Dyck, R., Bitter, M., Heins, R., Onstein, E. J., & Eisen, B. (1992). Spouse-aided therapy with agoraphobics. British Journal of Psychiatry, 160, 51–56.

    Article  PubMed  Google Scholar 

  • Emmelkamp, P. M. G., & Vedel, E. (2002). Spouse-aided therapy. In Hersen, M., & Sledge, W. (Eds.), The encyclopedia of psychotherapy, Vol. II. New York: Academic, 693–698.

    Chapter  Google Scholar 

  • Emmelkamp, P. M. G., & Vedel, E. (2006). Evidence-based treatment of alcohol and drug abuse: A practitioners guide to theory, research and treatment. New York: Routledge/Taylor & Francis.

    Google Scholar 

  • Falls, W. A., Miserendino, M. J., & Davis, M. (1992). Extinction of fear-potentiated startle: Blockade by infusion of an NMDA antagonist into the amygdala. Journal of Neuroscience, 12(3), 854–863.

    PubMed  Google Scholar 

  • Fanner, D., & Urquhartt, C. (2008). Bibliotherapy for mental health service users Part 1: A systematic review. Health Information and Libraries Journal, 25, 237–252.

    Article  PubMed  Google Scholar 

  • Faravelli, C., & Pallanti, S. (1989). Recent live events and panic disorder. American Journal of Psychiatry, 146, 622–626.

    PubMed  Google Scholar 

  • Fava, G. A., Rafanelli, C., Grandi, S., Conti, S., Ruini, C., Mangelli, L., et al. (2001). Long-term outcome of panic disorder with agoraphobia treated by exposure. Psychological Medicine, 31, 891–898.

    PubMed  Google Scholar 

  • Feldner, M. T., Zvolensky, M. J., & Leen-Feldner, E. W. (2004). A critical review of the empirical literature on coping and panic disorder. Clinical Psychology Review, 24, 123–148.

    Article  PubMed  Google Scholar 

  • First, M. B., Spitzer, R. L., & Gibbon, M. (1994). Structured clinical interview for DSM-IV disorders, SCID-I. New York: Biometrics Research.

    Google Scholar 

  • First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (1996). Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I, Research version). New York: Biometric Research Department.

    Google Scholar 

  • Foa, E. B., Grayson, J. B., Steketee, G. S., Doppelt, H. G., Turner, R. M., & Latimer, P. R. (1983). Success and failure in the behavioral treatment of obsessive-compulsives. Journal of Consulting and Clinical Psycholgy, 51(2), 287–297.

    Article  Google Scholar 

  • Foa, E. B., & Kozak, M. J. (1986). Emotional processing of fear: Exposure to corrective information. Psychological Bulletin, 99(1), 20–35.

    Article  PubMed  Google Scholar 

  • Foa, E. B., & McNally, R. J. (1996). Mechanisms of change in exposure therapy. In Rapee, R. M. (Ed.), Current controversies in the anxiety disorders (pp. 329–343). New York: Guilford.

    Google Scholar 

  • Furukawa, T. A., Watanabe, N., & Churchill, R. (2007). Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia. Cochrane Database Systematic Reviews, 24(1), CD004364.

    Google Scholar 

  • Ghane, S., Kolk, A. M., & Emmelkamp, P. M. G. (in press). Assessment of explanatory models of mental illness: Effects of patient and interviewer characteristics. Social Psychiatry and Psychiatric Epidemiology.

    Google Scholar 

  • Gladsjo, J. A., Rapaport, M. H., McKinney, R., Auerbach, M., Hahn, T., Rabin, A., et al. (2001). Absence of neuropsychologic deficits in patients receiving long-term treatment with alprazolam-XR for panic disorder. Journal of Clinical Psychopharmacology, 21(2), 131–138.

    Article  PubMed  Google Scholar 

  • Goldstein, A. J., & Chambless, D. L. (1978). A reanalysis of agoraphobia. Behavior Therapy, 9, 47–59.

    Article  Google Scholar 

  • Gonzalez-Lima, F., & Bruchey, A. K. (2004). Extinction memory improvement by the metabolic enhancer methylene blue. Learning and Memory, 11(5), 633–640.

    Article  PubMed  Google Scholar 

  • Gould, R. A., & Clum, G. A. (1995). Self-help plus minimal therapist contact in the treatment of panic disorder: A replication and extension. Behavior Therapy, 26, 533–546.

    Article  Google Scholar 

  • Gould, R. A., Otto, M. W., & Pollack, M. H. (1995). A meta-analysis of treatment outcome for panic disorder. Clinical Psychology Review, 15, 819–844.

    Article  Google Scholar 

  • Grant, B. F., Stinson, F. S., Dawson, D. A., Chou, S. P., Dufour, M. C., Compton, W., et al. (2004). Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders. Archives of General Psychiatry, 61, 807–816.

    Article  PubMed  Google Scholar 

  • Gunther, L. M., Denniston, J. C., & Miller, R. R. (1998). Conducting exposure treatment in multiple contexts can prevent relapse. Behaviour Research and Therapy, 36(1), 75–91.

    Article  PubMed  Google Scholar 

  • Hazen, A. L., Walker, J. R., & Eldridge, G. D. (1996). Anxiety sensitivity and treatment outcome in panic disorder. Anxiety, 2, 34–39.

    Article  PubMed  Google Scholar 

  • Hecker, J. E., Losee, M. C., Roberson-Nay, R., & Maki, K. (2004). Mastery of your anxiety and panic and brief therapist contact in the treatment of panic disorder. Journal of Anxiety Disorders, 18, 111–126.

    Article  PubMed  Google Scholar 

  • Hegel, M. T., Lewis Ravaris, C., & Ahles, T. A. (1994). Combined cognitive-behavioral and time-limited alprazolam treatment of panic disorder. Behavior Therapy, 25(2), 183–195.

    Article  Google Scholar 

  • Hoffart, A. (1995). A comparison of cognitive and guided mastery therapy of agoraphobia. Behaviour Research and Therapy, 33, 423––434.

    Article  PubMed  Google Scholar 

  • Hoffart, A., & Martinsen, E. W. (1990). Exposure-based integrated vs. pure psychodynamic treatment of agoraphobic inpatients. Psychotherapy, 27, 210–218.

    Article  Google Scholar 

  • Hofmann, S. G., Meuret, A. E., Smits, J. A., Simon, N. M., Pollack, M. H., Eisenmenger, K., et al. (2006). Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Archives of General Psychiatry, 63(3), 298–304.

    Article  PubMed  Google Scholar 

  • Houck, P. R., Spiegel, D. A., Shear, K., & Rucci, P. (2002). Reliability of the self-report version of the panic disorder severity scale. Depression and Anxiety, 15, 183–185.

    Article  PubMed  Google Scholar 

  • Hunsley, J., & Lee, C. M. (2007). Research-informed benchmarks for psychological treatments: Efficacy studies, effectiveness studies, and beyond. Professional Psychology, Research & Practice, 38, 21–33.

    Article  Google Scholar 

  • Ietsugu, T., Sukigara, M., & Furukawa, T. A. (2007). Evaluation of diagnostic criteria for panic attack using item response theory: Findings from the national comorbidity survey in USA. Journal of Affective Disorders, 104, 197–201.

    Article  PubMed  Google Scholar 

  • Kamphuis, J. H., & Telch, M. J. (2000). Effects of distraction and guided threat reappraisal on fear reduction during exposure-based treatments for specific fears. Behaviour Research and Therapy, 38, 1163–1181.

    Article  PubMed  Google Scholar 

  • Kessler, R. C., Crum, R. M., Warner, L. A., Nelson, C. B., Schulenberg, J., & Anthony, J. C. (1997). The lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the national comorbidity survey. Archives of General Psychiatry, 54, 313–321.

    Article  PubMed  Google Scholar 

  • Khawaja, N. G., & Oei, T. P. S. (1992). Development of a Catastrophic cognition questionnaire. Journal of Anxiety Disorders, 6, 305–318.

    Article  Google Scholar 

  • Kingdon, D., Tyrer, P., Seivewright, N., Ferguson, B., & Murphy, S. (1996). The Nottingham study of neurotic disorders: Influence of cognitive therapists on outcome. British Journal of Psychiatry, 169, 93–97.

    Article  PubMed  Google Scholar 

  • Kiropoulos, L. A., Klein, B., Austin, D. W., Gilson, K., Pier, C., Mitchell, J., & Ciechomski, L. (2008). Is Internet-based CBT for panic disorder and agoraphobia as effective as face-to-face CBT? Journal of Anxiety Disorders, 22, 1273–1284.

    Article  PubMed  Google Scholar 

  • Klass, E. T., Milrod, B. L., Leon, A. C., Kay, S. J., Schwalberg, M., Li, C., & Markowitz, J. C. (2009). Does interpersonal loss preceding panic disorder onset moderate response to psychotherapy? An exploratory study. Journal of Clinical Psychiatry (in press).

    Google Scholar 

  • Klein, B., Richards, J. C., & Austin, D. W. (2006). Efficacy of internet therapy for panic disorder. Journal of Behav-ior Therapy and Experimental Psychiatry, 37, 213–238.

    Article  Google Scholar 

  • Klosko, J. S., Barlow, D. H., Toussinari, R. B., & Cerny, J. A. (1990). A comparison of alprazolam and behavior therapy in the treatment of panic disorder. Journal of Consulting and Clinical Psychology, 58, 805–810.

    Article  Google Scholar 

  • Kozak, M. J., Foa, E. B., & Steketee, G. (1988). Process and outcome of exposure treatment with obsessive-compulsives: Psychophysiological indicators of emotional processing. Behavior Therapy, 19, 157–169.

    Article  Google Scholar 

  • Kushner, M. G., Kim, S. W., Donahue, C., Thuras, P., Adson, D., Kotlyar, M., et al. (2007). D-cycloserine augmented exposure therapy for obsessive-compulsive disorder. Biological Psychiatry, 62, 835–838.

    Article  PubMed  Google Scholar 

  • Lelliott, P. T., Marks, I. M., Monteiro, W. O., Tsakiris, F., & Noshirvani, H. (1987). Agoraphobia 5 years after imipramine and exposure: Outcome and prediction. Journal of Nervous and Mental Disease, 175, 599–605.

    Article  PubMed  Google Scholar 

  • Marcaurelle, R., Bélanger, C., & Marchand, A. (2003). Marital relationship and the treatment of panic disorder with agoraphobia: A critical review. Clinical Psychology Review, 23, 247–276.

    Article  PubMed  Google Scholar 

  • Marchand, M., Coutu, M. F., Dupuis, G., Fleet, R., Borgeat, B., Todorov, C., et al. (2008). Treatment of panic disorder with agoraphobia: Randomized placebo-controlled trial of four psychosocial treatments combined with imipramine or placebo. Cognitive Behavior Therapy, 37, 146–159.

    Article  Google Scholar 

  • Marks, I., Swinson, R. P., Basoglu, M., Kuch, K., Noshirvani, H., O’Sullivan, G., et al. (1993). Alprazolam and exposure alone and combined in panic disorder with agoraphobia. A controlled study in London and Toronto. British Journal of Psychiatry, 162, 776–787.

    Article  PubMed  Google Scholar 

  • Mathew, S. J., Price, R. B., & Charney, D. S. (2008). Recent advances in the neurobiology of anxiety disorders: Implications for novel therapeutics. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, 148(2), 89–98.

    Article  Google Scholar 

  • Michelson, L., Mavissakalian, M., & Marchione, K. (1988). Cognitive, behavioral and psychophysiological treatments of agoraphobia: A comparative outcome investigation. Behavior Therapy, 19, 97–120.

    Article  Google Scholar 

  • Milrod, B., Leon, A. C., Busch, F., Shapiro, T., Aronson, A., & Roiphe, J., et al. (2007). A randomized controlled clinical trial of psychoanalytic psychotherapy for panic disorder. American Journal of Psychiatry, 164, 265–272.

    Article  PubMed  Google Scholar 

  • Milrod, B., Leon, A. C., & Shear, M. K. (2004). Can interpersonal loss precipitate panic disorder? American Journal of Psychiatry, 161, 758–759.

    Article  PubMed  Google Scholar 

  • Mineka, S. (1985). Animal models of anxiety-based disorders: Their usefulness and limitations. In Tuma, A. H., & Maser, J. D. (Eds.), Anxiety and the anxiety disorders. Hillside, NJ: Lawrence Erlbaum.

    Google Scholar 

  • Mohlman, J., & Zinbarg, R. E. (2000). What kind of attention is necessary for fear reduction? An empirical test of the emotional processing model. Behavior Therapy, 31, 113–133.

    Article  Google Scholar 

  • Morris, R. W., & Bouton, M. E. (2007). The effect of yohimbine on the extinction of conditioned fear: A role for context. Behavioral Neuroscience, 121(3), 501–514.

    Article  PubMed  Google Scholar 

  • Mystkowski, J. L., Craske, M. G., Echiverri, A. M., & Labus, J. S. (2006). Mental reinstatement of context and return of fear in spider-fearful participants. Behavior Therapy, 37(1), 49–60.

    Article  PubMed  Google Scholar 

  • Mystkowski, J. L., Mineka, S., Vernon, L. L., & Zinbarg, R. E. (2003). Changes in caffeine states enhance return of fear in spider phobia. Journal of Consulting and Clinical Psychology, 71(2), 243–250.

    Article  PubMed  Google Scholar 

  • NIH. (1991). Treatment of panic disorder: NIH consensus statement. Retrieved on January 20, 2009, from http://consensus.nih.gov/1991/1991PanicDisorder085html.htm

  • NIH. (1992). NIH releases consensus statement on panic disorder. American Family Physician, 45(1), 261–262, 264.

    Google Scholar 

  • NIH. (1993). Treatment of panic disorder: Summary of the NIH consensus statement. Maryland Medical Journal, 42(3), 306–307.

    Google Scholar 

  • Norton, P. J., Zvolensky, M. J., Bonn-Miller, M. O., Cox, B. J., & Norton, G. R. (2008). Use of the panic attack questionnaire-IV (PAQ-IV) to assess non-clinical panic attacks and limited symptom panic attacks in student and community samples. Journal of Anxiety Disorders, 22, 1159–1171.

    Google Scholar 

  • Oei, T. P., Llamas, M., & Devilly, G. J. (1999). The efficacy and cognitive processes of cognitive behaviour therapy in the treatment of panic disorder with agoraphobia. Behavioural and Cognitive Psychotherapy, 27, 63–88.

    Google Scholar 

  • Otto, M. W., Pollack, M. H., & Sabatino, S. A. (1996). Maintenance of remission following cognitive behavior therapy for panic disorder: Possible deleterious effects of concurrent medication treatment. Behavior Therapy, 27, 473–482.

    Article  Google Scholar 

  • Otto, M. W., Pollack, M. H., Sachs, G. S., Reiter, S. R., Meltzer-Brody, S., & Rosenbaum, J. F. (1993). Discontinuation of benzodiazepine treatment: Efficacy of cognitive-behavioral therapy for patients with panic disorder. American Journal of Psychiatry, 150(10), 1485–1490.

    PubMed  Google Scholar 

  • O’Sullivan, G., & Marks, I. (1990). Long-term outcome of phobic and Obsessive-compulsive disorders after treatment. In Noyes, R., Roth, M., & Burrows, C. D. (eds.), Handbook of Anxiety, Vol. 4, pp. 87–108. Elsevier: Amsterdam.

    Google Scholar 

  • Patten, S. B., & Williams, J. V. A. (2007). Chronic obstructive lung diseases and prevalence of mood, anxiety, and substance-use disorders in a large population sample. Psychosomatics, 48, 496–501.

    Article  PubMed  Google Scholar 

  • Penfold, K., & Page, A. C. (1999). The effect of distraction on within-session anxiety reduction during brief in vivo exposure for mild blood-injection fears. Behavior Therapy, 30, 607–621.

    Article  Google Scholar 

  • Peter, H., Brückner, E., Hand, I., Rohr, W., & Rufer, M. (2008). Treatment outcome of female agoraphobics 3–9 years after exposure in vivo: A comparison with healthy controls. Journal of Behavior Therapy and Experimental Psychiatry, 39, 3–10.

    Article  PubMed  Google Scholar 

  • Peterson, R. A., & Reiss, S. (1987). Anxiety sensitivity index. Palos Heights, IL: International Diagnostic Systems.

    Google Scholar 

  • Peterson, R. A., & Reiss, S. (1993). Anxiety sensitivity index revised test manual. Worthington, OH: IDS.

    Google Scholar 

  • Pollard, A. C., Pollard, H. J., Corn, K. J. (1989). Panic onset and major events in the lives of agoraphobics: A test of contiguity. Journal of Abnormal Psychology, 3, 318–321.

    Article  Google Scholar 

  • Powers, M. B., & Emmelkamp, P. M. G. (2009). Dissemination of research findings. In Richard, D., & Huprick, S. (Eds.), Clinical psychology: Assessment, treatment and research (pp. 495–524). Burlington, MA: Elsevier.

    Google Scholar 

  • Powers, M. B., Smits, J. A. J., Otto, M. W., Sanders, C., & Emmelkamp, P. M. G. (2009). Facilitation of fear extinction in phobic participants with a novel cognitive enhancer: A randomized placebo controlled trial of yohimbine augmentation. Journal of Anxiety Disorders, 23, 350–356.

    Article  PubMed  Google Scholar 

  • Powers, M. B., Smits, J. A., & Telch, M. J. (2004). Disentangling the effects of safety-behavior utilization and safety-behavior availability during exposure-based treatment: A placebo-controlled trial. Journal of Consulting and Clinical Psychology, 72(3), 448–454.

    Article  PubMed  Google Scholar 

  • Powers, M. B., Smits, J. A. J., Whitley, D., Bystritsky, A., & Telch, M. J. (2008). The Effect of Attributional Processes Concerning Medication Taking on Return of Fear. Journal of Consulting and Clinical Psychology, 76(3), 478–490.

    Article  PubMed  Google Scholar 

  • Rachman, S. (1980). Emotional processing. Behavior Research and Therapy, 18(1), 51–60.

    Article  Google Scholar 

  • Rachman, S. (1994). The overprediction of fear: A review. Behaviour Research and Therapy, 32(7), 683–690.

    Article  PubMed  Google Scholar 

  • Rachman, S., Craske, M. G., Tallman, K., & Solyom, C. (1986). Does escape behavior strengthen agoraphobic avoidance? A replication. Behavior Therapy, 17, 366–384.

    Article  Google Scholar 

  • Raffa, S. D., White, K. S., & Barlow, D. H. (2004). Feared consequences of panic attacks in panic disorder: A qualitative and qualitative analysis. Cognitive Behaviour Therapy, 33, 199–207.

    Article  PubMed  Google Scholar 

  • Reiss, S., Peterson, R. A., Gursky, D. M., McNally, R. J. (1986). Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. Behaviour Research and Therapy, 24, 1–8.

    Article  PubMed  Google Scholar 

  • Rescorla, R. A., & Heth, C. D. (1975). Reinstatement of fear to an extinguished conditioned stimulus. Journal of Experimental Psychology: Animal Beha-viour Process, 1(1), 88–96.

    Article  Google Scholar 

  • Rescorla, R. A., & Wagner, A. R. (1972). A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. In Black, A. H., & Prokasy, W. F. (Eds.), Classical conditioning II: Current research and theory (pp. 64–99). New York: Appleton-Century-Crofts.

    Google Scholar 

  • Ressler, K. J., Rothbaum, B. O., Tannenbaum, L., Anderson, P., Graap, K., Zimand, E., et al. (2004). Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear. Archives of General Psychiatry, 61(11), 1136–1144.

    Article  PubMed  Google Scholar 

  • Ricker, S. T., & Bouton, M. (1996). Reacquisition following extinction in appetitive conditioning. Animal Learning and Behavior, 24, 423–436.

    Article  Google Scholar 

  • Rijken, H., Kraaimaat, F., de Ruiter, C., & Garssen, B. (1992). A follow-up study on short-term treatment of agoraphobia. Behaviour Research and Therapy, 30, 63–66.

    Article  PubMed  Google Scholar 

  • Rollman, B. L., Belnap, B. H., & Mazumdar, S., et al. (2005). A randomized trial to improve the quality of treatment for panic and generalized anxiety disorders in primary care. Archives of General Psychiatry, 62, 1332–1341.

    Article  PubMed  Google Scholar 

  • Rowe, M. K., & Craske, M. G. (1998). Effects of an expanding-spaced vs massed exposure schedule on fear reduction and return of fear. Behaviour Research and Therapy, 36(7–8), 701–717.

    Article  PubMed  Google Scholar 

  • Roy-Byrne, P., Russo, J., Dugdale, D. C., Lessler, D., Cowley, D., & Katon, W. (2002). Undertreatment of panic disorder in primary care: Role of patient and physician characteristics. Journal of the American Board of Family Medicine, 15(6), 443–450.

    Google Scholar 

  • Salkovskis, P. M. (1991). The importance of behaviour in the maintenance of anxiety and panic. Behavioural Psychotherapy, 19, 6–19.

    Article  Google Scholar 

  • Salkovskis, P. M., Jomes, D. R. G., & Clark, D. M. (1986). Respiratory control in the treatment of panic attacks: Replication and extension with concurrent measurement of behaviour and pCO2. British Journal of Psychiatry, 148, 526–532.

    Article  PubMed  Google Scholar 

  • Schadé, A., Marquenie, L. A., Van Balkom, A. J. L. M., Koeter, M. W. J., De Beurs, E., Van den Brink, W., et al. (2004). Alcohol-dependent patients with comorbid phobic disorders: A comparison between comorbid patients, pure alcohol-dependent and pure phobic patients. Alcohol and Alcoholism, 39, 241–246.

    Article  PubMed  Google Scholar 

  • Schadé, A., Marquenie, L. A., Van Balkom, A. J. L. M., Koeter, M. W. J., De Beurs, E., Van Dyck, R., et al. (2005). The effectiveness of anxiety treatment on alcohol-dependent patients with a comorbid phobic disorder: A randomized controlled trial. Alcoholism: Clinical and Experimental Research, 29, 794–800.

    Article  Google Scholar 

  • Schmidt, N. B., Wollaway-Bickel, K., Trakowski, J. H., Santiago, H. T., & Vasey, M. (2002). Antidepressant discontinuation in the context of cognitive behavioral treatment for panic disorder. Behaviour Research & Therapy, 40(1), 67–73.

    Article  Google Scholar 

  • Schmidt, N. B., Woolaway-Bickel, K., Trakowski, J., Santiago, H., Storey, J., Koselka, M., et al. (2000). Dismantling cognitive-behavioral treatment for panic disorder: Questioning the utility of breathing retraining. Journal of Consulting and Clinical Psychology, 68(3), 417–424.

    Article  PubMed  Google Scholar 

  • Schneider, A. J., Mataix-Cois, D., Marks, I. M., & Bachofen, M. (2005). Internet guided self-help with or without exposure therapy for phobic and panic disorders. Psychotherapy and Psychosomatics, 74, 154–164.

    Article  PubMed  Google Scholar 

  • Schneider, U., Altmann, A., Baumann, M., Bernzen, J., Bertz, B., Bimber, U., et al. (2001). Comorbid anxiety and affective disorder in alcohol-dependent patients seeking treatment: The first multicentre study in Germany. Alcohol and Alcoholism, 36, 219–223.

    Article  PubMed  Google Scholar 

  • Scocco, P., Barbieri, I., & Frank, E. (2007). Interpersonal problem areas and onset of panic disorder. Psychopathology, 40, 8–13.

    Article  PubMed  Google Scholar 

  • Scupi, B. S., Benson, B. E., Brown, L. B., & Uhde, T. W. (1997). Rapid onset: A valid panic disorder criterion? Depression and Anxiety, 5, 121–126.

    Article  PubMed  Google Scholar 

  • Sharp, D. M., Power, K. G., Simpson, R. J., Swanson, V., Moodie, E., Anstee, J. A., et al. (1996). Fluvoxamine, placebo, and cognitive behaviour therapy used alone and in combination in the treatment of panic disorder and agoraphobia. Journal of Anxiety Disorders, 10(4), 219–242.

    Article  Google Scholar 

  • Shear, M. K., Brown, T. A., Barlow, D. H., Money, R., Sholomskas, D. E., Woods, S. W., et al. (1997). Multicenter collaborative panic disorder severity scale. American Journal of Psychiatry, 154(11), 1571–1575.

    PubMed  Google Scholar 

  • Shear, M. K., Brown, T. A., Sholomskas, D. E., Barlow, D. H., Gorman, J. M., Woods, S. W. et al. (1992). Panic disorder severity scale (PDSS). Pittsburgh, PA: Department of Psychiatry, University of Pittsburgh School of Medicine.

    Google Scholar 

  • Shear, M. K., Pilkonis, P. A., Cloitre, M., & Leon, A. C. (1994). Cognitive behavioral treatment compared with nonprescriptive treatment of panic disorder. Archives of General Psychiatry, 53, 395–401.

    Article  Google Scholar 

  • Sheehan, D. V., Lecrubier, Y., Sheehan, K. H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R., & Dunbar, C. (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry, 59(suppl 20), 22–33.

    PubMed  Google Scholar 

  • Smits, J. A., Powers, M. B., Cho, Y., & Telch, M. J. (2004). Mechanism of change in cognitive-behavioral treatment of panic disorder: Evidence for the fear of fear mediational hypothesis. Journal of Consulting and Clinical Psychology, 72(4), 646–652.

    Article  PubMed  Google Scholar 

  • Spiegel, D. A., & Bruce, T. J. (1997). Benzodiazepines and exposure-based cognitive behavior therapies for panic disorder: Conclusions from combined treatment trials. American Journal of Psychiatry, 154, 773–781.

    PubMed  Google Scholar 

  • Spiegel, D. A., Bruce, T. J., Gregg, S. F., & Nuzzarello, A. (1994). Does cognitive behavior therapy assist slow-taper alprazolam discontinuation in panic disorder? American Journal of Psychiatry, 151(6), 876–881.

    PubMed  Google Scholar 

  • Spira, A. P., Zvolensky, M. J., Eifert, G. H., & Feldner, M. T. (2004). Avoidance-oriented coping as a predictor of panic-related distress: A test using biological challenge. Journal of Anxiety Disorders, 18, 309–323.

    Article  PubMed  Google Scholar 

  • Swinson, R. P., Fergus, K. D., Cox, B. J., Wickwire, K. (1995). Efficacy of telephone-administered behavioral therapy for panic disorder with agoraphobia. Behaviour Research & Therapy, 33, 465–469.

    Article  Google Scholar 

  • Taylor, C., King, R., Margraf, J., Ehlers, A., Telch, M., Roth, W., et al. (1989). Use of medication and in vivo exposure in volunteers for panic disorder research. American Journal of Psychiatry, 146(11), 1423–1426.

    PubMed  Google Scholar 

  • Taylor, S., Koch, W. J., & McNally, R. J. (1992). How does anxiety sensitivity vary across the anxiety disorders? Journal of Anxiety Disorders, 6(3), 249–259.

    Article  Google Scholar 

  • Telch, M. J. (1987). The panic appraisal inventory. Unpublished manuscript: University of Texas at Austin.

    Google Scholar 

  • Telch, M. J., Agras, W. S., Taylor, C. B., Roth, W. T., & Gallen, C. C. (1985). Combined pharmacological and behavioral treatment for agoraphobia. Behaviour Research and Therapy, 23, 325–335.

    Article  PubMed  Google Scholar 

  • Telch, M. J., Brouillard, M., Telch, C. F., Agras, W. S., & Taylor, C. B. (1989). Role of cognitive appraisal in panic-related avoidance. Behaviour Research and Therapy, 27(4), 373–383.

    Article  PubMed  Google Scholar 

  • Teusch, L., Böhme, H., & Gastpar, M. (1997). The benefit of an insight-oriented and experiential approach on panic and agoraphobia symptoms. Psychotherapy and Psychosomatics, 66, 293–301.

    Article  PubMed  Google Scholar 

  • Tsao, J. C., & Craske, M. G. (2000). Timing of treatment and return of fear: Effects of massed, uniform-, and expanding-spaced exposure schedules. Behavior Therapy, 31(3), 479–497.

    Article  Google Scholar 

  • Tsao, J. C., Lewin, M. R., & Craske, M. G. (1998). The Effects of Cognitive-Behavior Therapy for Panic Disorder on Comorbid Conditions. Journal of Anxiety Disorders, 12(4), 357–371.

    Article  PubMed  Google Scholar 

  • Tsao, J. C., Mystkowski, J. L., Zucker, B. G., & Craske, M. G. (2002). Effects of cognitive-behavioral therapy for panic disorder on comorbid conditions: Replication and extension. Behavior Therapy, 33(4), 493–509.

    Article  Google Scholar 

  • Tsao, J. C., Mystkowski, J. L., Zucker, B. G., & Craske, M. G. (2005). Impact of cognitive-behavioral therapy for panic disorder on comorbidity: A controlled investigation. Behaviour Research & Therapy, 43(7), 959–970.

    Article  Google Scholar 

  • van Balkom, A. J. L. M., Bakker, A., Spinhoven, P., Blaauw, B. M. J. W., Smeenk, S., & Ruesink, B. (1997). A meta-analysis of the treatment of panic disorder with or without agoraphobia: A comparison of psychopharmacological, cognitive-behavioral, and combination treatments. Journal of Nervous and Mental Disease, 185, 510–516.

    Article  PubMed  Google Scholar 

  • van Balkom, A. J. L. M., Nauta, M. C. E., & Bakker, A. (1995). Meta-analysis on the treatment of panic disorder with agoraphobia: Review and re-examination. Clinical Psychology and Psychotherapy, 2, 1–14.

    Article  Google Scholar 

  • Van den Hout, M., Arntz, A., & Hoekstra, R. (1994). Exposure reduced agoraphobia but not panic, and cognitive therapy reduced panic but not agoraphobia. Behaviour Research and Therapy, 32, 447–451.

    Article  PubMed  Google Scholar 

  • van der Molen, G. M., van den Hout, M. A., & Halfens, R. (1988). Agoraphobia and Locus of Control. Journal of Psychopathology and Behavioral Assessment, 10, 269–275.

    Article  Google Scholar 

  • van Hout, W. J. P. J., & Emmelkamp, P. M. G. (2002). Exposure in vivo. In Hersen, M., & Sledge, W. (Eds.), The Encyclopedia of Psychotherapy. New York: Academic.

    Google Scholar 

  • van Hout, W. J. P. J., Emmelkamp, P. M. G., Koopmans, P. C., Bögels, S. M., & Bouman, T. K. (2001). Assessment of self-statements in agoraphobic situations: Construction and psychometric evaluation of the Agoraphobic Self-statements Questionnaire (ASQ). Journal of Anxiety Disorders, 15, 183–201.

    Article  PubMed  Google Scholar 

  • van Hout, W. J. P. J., Emmelkamp, P. M. G., & Scholing, A. (1994). The role of negative self-statements in agoraphobic situations: A process study of eight panic disorder patients with agoraphobia. Behavior Modification, 18, 389–410.

    Article  PubMed  Google Scholar 

  • Vansteenwegen, D., Vervliet, B., Iberico, C., Baeyens, F., Van den Bergh, O., & Hermans, D. (2007). The repeated confrontation with videotapes of spiders in multiple contexts attenuates renewal of fear in spider-anxious students. Behaviour Research and Therapy, 45(6), 1169–1179.

    Article  PubMed  Google Scholar 

  • Vervliet, B. (2008). Learning and memory in conditioned fear extinction: Effects of D-cycloserine. Acta Psycholiga, 127(3), 601–613.

    Article  Google Scholar 

  • Watanabe, N., Churchill, R., & Furukawa, T. A. (2007). Combination of psychotherapy and benzodiazepines versus either therapy alone for panic disorder: A systematic review. BMC, Psychiatry, 7, 18.

    Article  Google Scholar 

  • Weiser, E. B. (2007). The prevalence of anxiety disorders among adults with asthma: A meta-analytic review. Journal of Clinical Psychology in Medical Settings, 14, 297–307.

    Article  Google Scholar 

  • Wells, A., Clark, D. M., Salkovskis, P., Ludgate, J., Hackmann, A., & Gelder, M. (1995). Social phobia: The role of in-situation safety behaviors in maintaining anxiety and negative beliefs. Behavior Therapy, 26(1), 153–161.

    Article  Google Scholar 

  • Whittal, M. L., Otto, M. W., & Hong, J. J. (2001). Cognitive-behavior therapy for discontinuation of SSRI treatment of panic disorder: A case series. Behavior Research and Therapy, 39(8), 939–945.

    Article  Google Scholar 

  • WHO. (1997). Composite International Diagnostic Interview (CIDI) researcher’s manual. Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Williams, S. L., & Falbo, J. (1996). Cognitive and per-formance-based treatments for panic attacks in people with varying degrees of agoraphobic disability. Behaviour Research and Therapy, 34, 253–264.

    Article  PubMed  Google Scholar 

  • Williams, S. L., & Zane, G. (1989). Guided mastery and stimulus exposure treatments for severe performance anxiety in agoraphobics. Behaviour Research and Therapy, 27, 237–245.

    Article  PubMed  Google Scholar 

  • Wolitzky, K. B., & Telch, M. J. (2009). Augmenting in vivo exposure with fear antagonistic actions: A preliminary test. Behavior Therapy, 40, 57–71.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media LLC

About this entry

Cite this entry

Emmelkamp, P.M.G., Powers, M.B. (2010). Agoraphobia. In: Thomas, J.C., Hersen, M. (eds) Handbook of Clinical Psychology Competencies. Springer, New York, NY. https://doi.org/10.1007/978-0-387-09757-2_26

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-09757-2_26

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-09756-5

  • Online ISBN: 978-0-387-09757-2

  • eBook Packages: Behavioral Science

Publish with us

Policies and ethics