Skip to main content

Rothman-Makai syndrome

  • Reference work entry
  • 16 Accesses

Part of the A to Z Essentials book series (ATOZ)

Synonym(s)

Lipogranulomatosis subcutanea; adipone-crosis subcutanea; lipophagic panniculitis of childhood

Definition

Panniculitis of children, characterized by subcutaneous nodules without systemic signs or symptoms

Pathogenesis

May be a variant of Weber-Christian disease; mechanism of disease unknown

Clinical manifestation

Well-demarcated, somewhat painful, symmetrical subcutaneous nodules, most often on lower extremities and trunk; atrophy in lesions of lipophagic panniculitis variant

Differential diagnosis

Thrombophlebitis; vasculitis; sarcoidosis; alpha-1 antitrypsin deficiency panniculitis; polyarteritis nodosa; eosinophilic fasciitis; eosinophilic myalgia syndrome; erythema induratum; erythema nodosum; leukemia; lipodermatosclerosis; lymphoma; pancreatic panniculitis; poststeroid panniculitis; scleroderma panniculitis; cytophagic histiocytic panniculitis; Sweet's syndrome

Therapy

No therapy indicated

This is a preview of subscription content, access via your institution.

References

  • Requena L, Sanchez Yus E (2001) Panniculitis. Part II. Mostly lobular panniculitis. Journal of the American Academy of Dermatology 45(3):325–361

    PubMed  CrossRef  CAS  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and Permissions

Copyright information

© 2004 Springer-Verlag

About this entry

Cite this entry

(2004). Rothman-Makai syndrome. In: Levine, N., Levine, C.C. (eds) Dermatology Therapy. A to Z Essentials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29668-9_2366

Download citation

  • DOI: https://doi.org/10.1007/3-540-29668-9_2366

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00864-4

  • Online ISBN: 978-3-540-29668-3

  • eBook Packages: Springer Book Archive