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Calcium pyrophosphate dihydrate deposition disease

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Synonyms

CPPDD, pseudogout, pyrophosphate arthropathy, chronic pyrophosphate arthropathy.

Definition

Calcium pyrophosphate dihydrate deposition disease is an arthritis syndrome with many clinical subtypes, including both inflammatory and non-inflammatory arthropathy. The most widely known subtype, termed pseudogout for its close resemblance to gouty arthritis, is characterized by acute episodes of painful, swollen joints, typically involving large joints such as the knee, wrist, or shoulder. Pseudogout attacks are often observed complicating other conditions in hospitalized patients. CPPDD that develops in the 1st MTP (metatarsophalangeal joint) is called pseudopodagra. CPPDD may also present as a chronic arthropathy. In older patients in which a powerful inflammatory response is observed, chronic pyrophospharte arthropathy can mimic rheumatoid arthritis. When localized to one or a few joints, CPPDD can cause syndromes as diverse as sacroileitis or Milwaukee...

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  • DOI: 10.1007/3-540-29662-X_533
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© 2004 Springer-Verlag

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(2004). Calcium pyrophosphate dihydrate deposition disease. In: Moreland, L.W. (eds) Rheumatology and Immunology Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29662-X_533

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  • DOI: https://doi.org/10.1007/3-540-29662-X_533

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20625-5

  • Online ISBN: 978-3-540-29662-1

  • eBook Packages: Springer Book Archive