Synonyms
Passive cutaneous anaphylaxis.
Definition
The induction of hypersensitivity responsiveness to a naive recipient by administration of serum containing specific IgE followed by allergen challenge.
Full Text
This method is of historical importance because it demonstrated the ability to transfer immediate hypersensitivity through serum, indicating that antibodies mediated the response. Current use of the method is restricted to animal experiments performed to elucidate the inflammatory pathways of immediate hypersensitivity responses.
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References
Spiegelberg HL (1976) Principles of methods. In: Miescher PA, Muller-Eberhard HJ (eds) Textbook of Immunopathology. Grune & Stratton, New York, pp 1101–18
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© 2004 Springer-Verlag
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(2004). Passive anaphylaxis. In: Moreland, L.W. (eds) Rheumatology and Immunology Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29662-X_2100
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DOI: https://doi.org/10.1007/3-540-29662-X_2100
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-20625-5
Online ISBN: 978-3-540-29662-1
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