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Monosodium urate crystals

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Synonyms

Gout crystals, MSU crystals, monosodium urate monohydrate crystals.

Definition

Crystals of monosodium urate are needle-shaped, 5–25 μm in length, and strongly negatively birefringent under polarized light. Crystallization of monosodium urate in synovial fluid and tissues results in a dramatic inflammatory response characterized by erythema, edema, and intense pain. Gout is the term used to describe the symptoms and signs associated with the potent inflammatory response to MSU crystal deposition.

Table 1 Theories on MSU crystal formation in the synovial tissues

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© 2004 Springer-Verlag

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(2004). Monosodium urate crystals. In: Moreland, L.W. (eds) Rheumatology and Immunology Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29662-X_1891

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  • DOI: https://doi.org/10.1007/3-540-29662-X_1891

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-20625-5

  • Online ISBN: 978-3-540-29662-1

  • eBook Packages: Springer Book Archive

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