Reference work entry
DOI: https://doi.org/10.1007/3-540-29662-X_1306


A genetic or aquired condition characterized by abnormally low levels of complement proteins in the blood.

Full Text

Hypocomplementemia can result from genetically inherited deficiencies of one or more complement proteins, or from overt complement cascade activation. The latter is a common occurence in immune-complex diseases like systemic lupus erythematosus.


  1. Hebert LA, Cosio FG, Neff JC (1991) Diagnostic significance of hypocomplementemia. Kidney International 39:811–21PubMedGoogle Scholar

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