Hypermobility syndromes

Reference work entry
DOI: https://doi.org/10.1007/3-540-29662-X_1293


Benign hypermobility syndrome.


The occurrence of musculoskeletal symptoms in patients with evidence of laxity in at least three joints, in the absence of other features of underlying systemic disease. Thought to be genetically determined in an autosomal dominant fashion, the syndrome likely represents a disorder of collagen that contributes to a loss of tensile strength and increased fragility of the involved tissues. Three of the following five criteria are required to demonstrate joint laxity: passive apposition of thumb to forearm, active hyperextension of elbow > 10 degrees, active hyperextension of knee > 10 degrees, passive hypertension of the metacarpal joints, and the ability to bend at the waist and place palms on the floor without bending the knees. Treatment of the hypermobility syndrome consists of explanation, muscle strengthening, joint protection, and symptomatic treatment with medication as needed.

Differential Diagnosis

Hereditable disorders of...

This is a preview of subscription content, log in to check access.


  1. Grahame R, Bird HA, Child A (2000) The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS). J Rheumatol 27:1777PubMedGoogle Scholar
  2. Finsterbush A, Pogrund H (1982) The hypermobility syndrome. Musculoskeletal complaints in 100 consecutive cases of generalized joint hypermobility. Clin Orthop (168):124–7Google Scholar

Copyright information

© Springer-Verlag 2004