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Definition

UTR stands for UnTranslated Region of an mRNA. An mRNA can be divided into the 5'untranslated region, the Open reading frame (ORF) and the 3′ UTR. The UTRs do not encode protein information, but have regulatory functions. Sequence motifs define e.g. the localization of the mRNA in the cell, the stability of the mRNA, and the amount of protein that is supposed to be generated from the mRNA at a given time.

Cap-Independent Translational Control Full Length cDNA Sequencing

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© 2006 Springer-Verlag

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(2006). UTR. In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-29623-9_9092

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