Lactate dehydrogenase (LDH) and adenylate kinase (AK) are both enzymes which are essential for normal cell metabolism. Upon cell damage these proteins are released from the cytosol into the cell culture medium. There, the activity of these enzymes is detected with special measurement procedures and can finally be used as non-destructive parameters for the determination of cytotoxicity.
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© 2005 Springer-Verlag
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(2005). Lactate Dehydrogenase (LDH) and/or Adenylate Kinase (AK) Leakage. In: Vohr, HW. (eds) Encyclopedic Reference of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27806-0_866
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DOI: https://doi.org/10.1007/3-540-27806-0_866
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-44172-4
Online ISBN: 978-3-540-27806-1
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