Adaptors are molecular scaffolds that recruit other proteins. These proteins contain two or more domains (i.e. SH2 and SH3 domains) which bind other proteins. They mediate protein-protein interactions but usually have no intrinsic kinase activity. In lymphocytes, adaptors recruit other proteins to the activated receptor where these proteins can be phosphorylated and activated.
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© 2005 Springer-Verlag
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(2005). Adaptors. In: Vohr, HW. (eds) Encyclopedic Reference of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27806-0_19
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DOI: https://doi.org/10.1007/3-540-27806-0_19
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-44172-4
Online ISBN: 978-3-540-27806-1
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