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A surface that allows massive activation of C3 and covalent binding of C3b. A nonactivator surface such as a host cell limits this activation using the normal control mechanisms of the complement system (e.g. factor H, CR1, presence of sialic acid).

Complement, Classical Pathway/Alternative Pathway

Complement System

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© 2005 Springer-Verlag

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(2005). Activator Surface. In: Vohr, HW. (eds) Encyclopedic Reference of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27806-0_10

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