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The Genus Helicobacter

  • Jay V. Solnick
  • Jani L. O’rourke
  • Peter Vandamme
  • Adrian Lee

Historical Background

Spiral-shaped bacteria were first seen in human gastric mucosa early in the twentieth century (Krienitz, 1906) and were subsequently described by several investigators (reviewed in Marshall, 1989). Similar organisms were also seen in the gastric mucosa of dogs, cats and a variety of other animals (Rappin, 1881; Bizzozero, 1892; Salomon, 1896; Lim, 1920; Doenges, 1939). The significance of these organisms was alternately debated and forgotten until Marshall and Warren isolated a Gram-negative, microaerophilic bacterium from human gastric biopsies and proposed that the organism may be the cause of chronic gastritis and peptic ulcer disease (Marshall and Warren, 1984a). The bacterium was thought originally to be a member of the genus Campylobacter and named “Campylobacter pyloridis,” later corrected to “Campylobacter pylori.” Subsequent 16S rRNA sequence analysis showed that the distance between the true campylobacters and C. pyloriwas sufficient to exclude it from...

Keywords

Pylorus Infection Nalidixic Acid Microaerobic Condition Indoxyl Acetate Sheath Flagellum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag 2006

Authors and Affiliations

  • Jay V. Solnick
  • Jani L. O’rourke
  • Peter Vandamme
  • Adrian Lee

There are no affiliations available

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