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The Prokaryotes pp 1119–1132Cite as

The Genus Francisella

  • SECTION 3.3 Gamma Subclass
  • Reference work entry
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Introduction

Francisella tularensis is best known as the zoonotic, highly infectious etiologic agent of the human disease, tularemia. There are three recognized species in the genus Francisella: F. tularensis, F. novicida, and F. philomiragia. All three species can cause human infections, although F. novicida and F. philomiragia rarely do. Disease caused by F. tularensis can be mild but it usually is acute, severe and febrile; infection with a common North American strain can be life threatening.

Phylogeny

Analysis of the 16S rRNA of Francisella species places them in the λ-subclass of the Proteobacteria (Forsman, 1994). All of the Francisella are closely related (98.5 to 99.9% sequence identity in the 16S rDNA sequence) and form a group together with Wobachia persica (97.85 identity) (Forsman, 1994). Recently, two groups discovered endosymbionts of the tick species, Ornithodoros moubata (Noda, 1997) and Dermacantor andersoni (Niebylski, 1997) that could be placed in the Francisella...

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Authors
  1. Francis Nano
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  2. Karen Elkins
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Editor information

Editors and Affiliations

  1. Department of Microbiology University of Minnesota, University of Minnesota, 196, Minneapolis, MN, 55455-0312, USA

    Martin Dworkin

  2. Department of Microbiology and Immunology, Stanford University Medical School, 299 Campus Drive, Fairchild, Stanford, CA, 94305-5124, USA

    Stanley Falkow

  3. Department of Molecular Microbiology and Biotechnology, Tel Aviv University, 69978, Ramat-Aviv, Israel

    Eugene Rosenberg

  4. Department of Microbiology, Technical University Munich, 80290, Munich, Germany

    Karl-Heinz Schleifer

  5. DSMZ-German Collection of Microorganisms and Cell Cultures GmbH, Mascheroder Weg 1b, 38124, Braunschweig, Germany

    Erko Stackebrandt

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© 2006 Springer-Verlag

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Nano, F., Elkins, K. (2006). The Genus Francisella. In: Dworkin, M., Falkow, S., Rosenberg, E., Schleifer, KH., Stackebrandt, E. (eds) The Prokaryotes. Springer, New York, NY. https://doi.org/10.1007/0-387-30746-X_44

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