Sydney Centenarian Study
This entry discusses the history, protocol, methodology, and initial outcomes of the Sydney Centenarian Study, a longitudinal study of cognitive and physical function of people aged 95 years or more. Difficulties of research involving very elderly participants are discussed as well as future directions for the project.
The global centenarian population is rapidly increasing (Richmond 2008), which has raised concerns about the burden this demographic change might have on health-care systems. At the same time, there is growing enthusiasm about the attainability of exceptional old age as well as longer productivity in the workforce and a focus on the role of modifiable, environmental factors in aging. As part of a growing wave of research into the very old, the Sydney Centenarian Study(SCS) was launched in 2007 at The University of New South Wales (UNSW), Australia. The SCS was developed to explore the genetic and environmental factors that contribute to...
- Gondo, Y., & Poon, L. W. (2008). Cognitive function of centenarians and its influence on longevity. In L. W. Poon & T. Perls (Eds.), Annual review of gerontology and geriatrics (Vol. 27, pp. 129–150). New York: Springer.Google Scholar
- Sachdev, P. S., Brodaty, H., Reppermund, S., Kochan, N. A., Trollor, J. N., Slavin, M. J., Crawford, J., Kang, K., Broe, G. A., Mather, K. A., & Lux, O. (2010). The Sydney memory and ageing study (MAS): Methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70–90 years. International Psychogeriatrics, 22(8), 1248–1264.PubMedCrossRefGoogle Scholar
- Sachdev, P. S., Levitan, C., Crawford, J., Sidhu, M., Slavin, M., Richmond, R., Kochan, N., Brodaty, H., Wen, W., Kang, K., & Mather, K. A. (2013). The Sydney centenarian study: Methodology and profile of centenarians and near-centenarians. International Psychogeriatrics, 25(6), 993–1005.PubMedCrossRefGoogle Scholar
- Song, F., Poljak, A., Crawford, J., Kochan, N. A., Wen, W., Cameron, B., Lux, O., Mather, K., Smythe, G. A., & Sachdev, P. S. (2012). Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals. PloS One, 7, e34078.PubMedPubMedCentralCrossRefGoogle Scholar
- Yang, Z., Wen, W., Jiang, J., Crawford, J. D., Reppermund, S., Levitan, C., Slavin, M. J., Kochan, N. A., Richmond, R. L., Brodaty, H., Trollor, J. N., & Sachdev, P. S. (2016). Age-associated differences on structural brain MRI in non-demented individuals from 71 to 103 years. Neurobiology Aging, S0197-4580(16)00007-5.Google Scholar