Abstract
Nanozymes are new-generation nanoproducts having enzyme-like catalytic properties and highly efficient than the native enzymes. As the catalytic mechanism of nanozymes is gradually revealed, the application fields of nanozymes have also been extensively explored. Recently, developments on nanozymes have made a remarkable progress and attracted a lot of researchers to explore their biomedical applications. Compared to the native enzymes, the nanozymes are highly beneficial due to their better stability, easy production, surface functionalization, reusability, and lower manufacturing costs. Moreover, the functionality of nanozymes can be remotely controlled by various physical factors including magnetic fields, ultrasound, light, and heat. In general, these factors can be regulated to advance the diagnosis and treatment of different diseases in the biomedical environment. Considering the huge potential of nanozymes in diagnosis and treatment (such as biological detection or biosensing, antibacterial, antioxidant, bioorthogonal chemistry, anti-inflammatory treatment, and cancer therapy), wide biological applications of different nanozymes are summarized in this chapter. Also, the factors that affect the properties of nanozymes (such as pH temperature, surface modification, and doping of other elements) are discussed. This chapter will enable the researchers to understand better the recent status of nanozymes and may help for new breakthroughs. At the end of this chapter, the prospects and challenges of using nanozymes in practical applications are discussed.
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Krishna Bayineni, V., Naira, V.R., Kadeppagari, RK. (2021). Biomedical Applications of Nanozymes: Disease Diagnosis and Therapy. In: Handbook of Consumer Nanoproducts. Springer, Singapore. https://doi.org/10.1007/978-981-15-6453-6_91-1
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DOI: https://doi.org/10.1007/978-981-15-6453-6_91-1
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