Biofilms in Microfluidic Devices
- Suresh NeethirajanAffiliated withSchool of Engineering, University of Guelph Email author
- , David KarigAffiliated withCenter for Nanophase Materials Sciences, Oak Ridge National Laboratory
- , Aloke KumarAffiliated withBiosciences Division, Oak Ridge National Laboratory
- , Partha P. MukherjeeAffiliated withComputer Science and Mathematics Division, Oak Ridge National Laboratory
- , Scott T. RettererAffiliated withBiosciences Division, Oak Ridge National Laboratory
- , Mitchel J. DoktyczAffiliated withCenter for Nanophase Materials Sciences, Oak Ridge National LaboratoryBiosciences Division, Oak Ridge National Laboratory
Biofilms are aggregations of microbes that are encased by extracellular polymeric substances (EPS) and adhere to surfaces or interfaces. Biofilms exist in a very wide diversity of environments, and microfluidic devices are being increasingly utilized to study and understand their formation and properties.
Microbes often form aggregates on interfaces, and due to a production of EPS, the aggregates become encased in a matrix . Though microbes in a biofilm are physiologically distinct from bacteria growing in a free swimming state (planktonic bacteria), biofilm growth is a complex process that is typically initiated by planktonic bacteria themselves. Biofilm growth is initiated with bacterial adhesion to a surface, followed by events such as growth, EPS secretion, and morphological and physiological changes. Microbial biofilms are excellent examples of multi-scale phenomena. Cell-to-cell communication, ...
Reference Work Entry Metrics
- Biofilms in Microfluidic Devices
- Reference Work Title
- Encyclopedia of Nanotechnology
- pp 213-219
- Print ISBN
- Online ISBN
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media B.V.
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- Editor Affiliations
- 1. Ohio Eminent Scholar and The Howard D. Winbigler Professor, Director, Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics (NLB2), Ohio State University
- Author Affiliations
- 04271. School of Engineering, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada
- 04272. Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, 1 Bethel Valley Road, 2008, Oak Ridge, TN, 37831, USA
- 04273. Biosciences Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, 2008, Oak Ridge, TN, 37831, USA
- 04274. Computer Science and Mathematics Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Mail Stop 6164, 2008, Oak Ridge, TN, 37831-6164, USA
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