Advertisement

Multifocal Choroiditis

  • Muhammad Hassan
  • Nam V. Nguyen
  • Yasir J. Sepah
  • Quan Dong Nguyen
Living reference work entry

Abstract

Idiopathic multifocal choroiditis (MFC) is a bilateral chronic progressive inflammatory chorioretinopathy affecting predominantly myopic Caucasian women with no known associated systemic or ocular diseases. The disease is characterized by yellowish-white lesions affecting posterior pole, periphery, or both. Active disease involves the outer retinal layers and retinal pigment epithelium (RPE) and spares the choroid. The vision-threatening complications of the disease include macular edema, choroidal neovascularization (CNV), and punched-out scars. Although there are no standard treatments, anti-inflammatory medications are prescribed in active stages to control the inflammation along with anti-vascular endothelial growth factor (anti-VEGF) agents in cases with CNV.

Suggested Reading

  1. Tavallali A, Yannuzzi LA. Idiopathic multifocal choroiditis. J Ophthalmic Vis Res. 2016;11(4):429–32.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Astroz P, Miere A, Mrejen S, Sekfali R, Souied EH, Jung C, et al. Optical coherence tomography angiography to distinguish choroidal neovascularization from macular inflammatory lesions in multifocal choroiditis. Retina. 2018;38(2):299–309.CrossRefPubMedGoogle Scholar
  3. Fung AT, Pal S, Yannuzzi NA, Christos P, Cooney M, Slakter JS, et al. Multifocal choroiditis without panuveitis: clinical characteristics and progression. Retina. 2014;34(1):98–107.CrossRefPubMedGoogle Scholar
  4. Jung JJ, Khan S, Mrejen S, Gallego-Pinazo R, Cunningham Jr ET, Freund KB, et al. Idiopathic multifocal choroiditis with outer retinal or chorioretinal atrophy. Retina. 2014;34(7):1439–50.CrossRefPubMedGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd., part of Springer Nature 2018

Authors and Affiliations

  • Muhammad Hassan
    • 1
  • Nam V. Nguyen
    • 1
  • Yasir J. Sepah
    • 1
  • Quan Dong Nguyen
    • 1
  1. 1.Byers Eye Institute at Stanford UniversityCaliforniaUSA

Personalised recommendations