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Posterior Segment Manifestations of Tuberculosis

  • Gaurav Gupta
  • Aniruddha Agarwal
  • Kanika Aggarwal
  • Vishali Gupta
Living reference work entry

Abstract

Intraocular tuberculosis may have protean clinical manifestations and often presents as a diagnostic challenge. The disease affects the posterior segment more frequently where it may manifest as choroidal granulomas, serpiginous-like choroiditis, retinal vasculitis, or subretinal abscesses. One of the phenotypes of ocular tuberculosis is a distinct type of posterior uveitis, termed as multifocal serpiginoid choroiditis (earlier referred to as serpiginous-like tuberculosis). This condition is characterized by serpentine choroidal lesions that bear resemblance to the autoimmune serpiginous choroiditis. The index chapter focuses on the clinical and imaging features, management, and complications of tubercular posterior uveitis.

Keywords

Ocular TB Serpiginous-like choroiditis Retinal vasculitis Tubercular uveitis Intermediate uveitis Tuberculoma 

Suggested Reading

  1. Agarwal A, Agrawal R, Khandelwal N, Invernizzi A, Aggarwal K, Sharma A, Singh R, Bansal R, Sharma K, Singh N, Gupta V. Choroidal structural changes in tubercular multifocal serpiginoid choroiditis. Ocul Immunol Inflamm. 2017a;11:1–7.CrossRefGoogle Scholar
  2. Agarwal A, Mahajan S, Khairallah M, Mahendradas P, Gupta A, Gupta V. Multimodal imaging in ocular tuberculosis. Ocul Immunol Inflamm. 2017b;25(1):134–45.CrossRefGoogle Scholar
  3. Aggarwal K, Agarwal A, Deokar A, Singh R, Bansal R, Sharma A, Sharma K, Dogra MR, Gupta V. Ultra-wide field imaging in paradoxical worsening of tubercular multifocal serpiginoid choroiditis after the initiation of anti-tubercular therapy. Ocul Immunol Inflamm. 2017;11:1–6.CrossRefGoogle Scholar
  4. Agrawal R, Gunasekeran DV, Grant R, Agarwal A, Kon OM, Nguyen QD, Pavesio C, Gupta V, Collaborative Ocular Tuberculosis Study (COTS)–1 Study Group. Clinical features and outcomes of patients with tubercular uveitis treated with antitubercular therapy in the collaborative ocular tuberculosis study (COTS)-1. JAMA Ophthalmol. 2017;135(12):1318–27.CrossRefGoogle Scholar
  5. Gupta A, et al. Classification of intraocular tuberculosis. Ocul Immunol Inflamm. 2014;14:1–7.Google Scholar
  6. Gupta V, et al. Clinics of ocular tuberculosis. Ocul Immunol Inflamm. 2015;23(1):14–24.CrossRefGoogle Scholar
  7. Gupta B, et al. Ocular manifestations of tuberculosis: an update. Expert Rev Ophthalmol. 2016;11(2):145–54.CrossRefGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd., part of Springer Nature 2018

Authors and Affiliations

  • Gaurav Gupta
    • 1
  • Aniruddha Agarwal
    • 1
  • Kanika Aggarwal
    • 1
  • Vishali Gupta
    • 1
  1. 1.Advanced Eye CenterPost Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

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