Retrograde Membrane Traffic and Recycling Endosome

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Abstract

Retrograde membrane traffic is where proteins and glycolipids are transported back from the plasma membrane (PM) and endosomes to the Golgi and is essential for a wide range of cellular functions. In recent years, studies have begun to show that recycling endosomes (REs), a specific class of endosomes, serve as intermediates for retrograde membrane traffic. In this review, the nature of retrograde membrane traffic that passes through REs and the molecules that regulate the traffic are summarized.

Keywords

Retrograde membrane traffic Recycling endosomes Shiga toxin Cholera toxin Glycolipid Evectin-2 SMAP2 Phosphatidylserine 
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Notes

Acknowledgments

Dr. Jenna E. McKenzie (the State of California Department of Pesticide Regulation) for the comments on the manuscript.

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Copyright information

© Springer Japan 2015

Authors and Affiliations

  1. 1.Department of BiochemistryOsaka University Graduate School of MedicineSuita, OsakaJapan
  2. 2.Pathological Cell Biology, Graduate School of Pharmaceutical SciencesUniversity of TokyoTokyoJapan

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