GLYCOSCIENCES.de started as one of the first online portals containing bioinformatics resources for glycobiology and glycomics. It consists of a variety of tools and databases that are connected to each other. Many of the applications are related to carbohydrate 3D structures, but other data sources such as MS or NMR are also supported. This chapter provides an overview of the available resources, their interconnections, and options to access and use the data.
Bioinformatics GLYCOSCIENCES.de 3D structure Glycan conformation Molecular modeling Data mining NMR MS data interpretation
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GLYCOSCIENCES.de was initially developed at the German Cancer Research Center Heidelberg in the research group of Claus-Wilhelm (“Willi”) von der Lieth. Unfortunately, he unexpectedly passed away in November 2007, which was a great loss to the glycoinformatics community. Most of the resources described in this chapter would not exist without him.
Bohne-Lang A, Lang E, Förster T, von der Lieth CW (2001) LINUCS: linear notation for unique description of carbohydrate sequences. Carbohydr Res 336:1–11CrossRefPubMedGoogle Scholar
Kumar S, Lütteke T, Schwartz-Albiez R (2012) GlycoCD: a repository for carbohydrate-related CD antigens. Bioinformatics 28:2553–2555CrossRefPubMedGoogle Scholar
Lohmann KK, von der Lieth CW (2004) GlycoFragment and GlycoSearchMS: web tools to support the interpretation of mass spectra of complex carbohydrates. Nucleic Acids Res 32:W261–W266CrossRefPubMedPubMedCentralGoogle Scholar
Loss A, Bunsmann P, Bohne A, Schwarzer E, Lang E, von der Lieth CW (2002) SWEET-DB: an attempt to create annotated data collections for carbohydrates. Nucleic Acids Res 30:405–408CrossRefPubMedPubMedCentralGoogle Scholar
Loss A, Stenutz R, Schwarzer E, von der Lieth CW (2006) GlyNest and CASPER: two independent approaches to estimate 1H and 13C NMR shifts of glycans available through a common web-interface. Nucleic Acids Res 34:W733–W737CrossRefPubMedPubMedCentralGoogle Scholar
Lütteke T, Frank M, von der Lieth CW (2005) Carbohydrate structure suite (CSS): analysis of carbohydrate 3D structures derived from the protein data bank. Nucleic Acids Res 33:D242–D246CrossRefPubMedPubMedCentralGoogle Scholar
Lütteke T, Bohne-Lang A, Loss A, Goetz T, Frank M, von der Lieth CW (2006) GLYCOSCIENCES.de: an internet portal to support glycomics and glycobiology research. Glycobiology 16:71R–81RCrossRefPubMedGoogle Scholar
Toukach P, Joshi HJ, Ranzinger R, Knirel Y, von der Lieth CW (2007) Sharing of worldwide distributed carbohydrate-related digital resources: online connection of the Bacterial Carbohydrate Structure DataBase and GLYCOSCIENCES.de. Nucleic Acids Res 35:D280–D286CrossRefPubMedPubMedCentralGoogle Scholar