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In-vitro-Maturation (IVM)

  • Thomas Strowitzki
  • Klaus Diedrich
  • Sabine Rösner
Living reference work entry
Part of the Springer Reference Medizin book series (SRM)

Zusammenfassung

Die In-vitro-Maturation (IVM) ist eine Technik der extracorporalen Befruchtung, bei der ohne oder nur mit kurzer niedrig dosierter kontrollierter ovarieller Überstimulation Eizellen gewonnen, in vitro nachgereift und anschließend fertilisiert werden. Hauptindikation besteht bei Frauen mit einem PCO-Syndrom zur Vermeidung eines ovariellen Überstimulationssyndroms. Die Schwangerschaftsraten erreichen die Erfolge der konventionellen In-vitro-Fertilisation. Obwohl theoretisch die beschleunigte In-vitro-Maturation sich negativ auswirken könnte, werden bislang keine erhöhten Fehlbildungsraten berichtet. Die erste Zweijahresnachbeobachtung zur mentalen Entwicklung von Kindern nach IVM hat im Vergleich zur In-vitro-Fertilisation (IVF) bzw. intrazytoplasmatischen Spermieninjektion (ICSI) keine Unterschiede ergeben. Zusammenfassend hat sich die IVM als Behandlungsmethode bei speziellen Risikokonstellationen bewährt.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  • Thomas Strowitzki
    • 1
  • Klaus Diedrich
    • 2
    • 3
  • Sabine Rösner
    • 1
  1. 1.Abt. für Gynäkologische Endokrinologie und FertilitätsstörungenUniversitätsklinikum Heidelberg FrauenklinikHeidelbergDeutschland
  2. 2.Facharzt-Zentrum für Kinderwunsch, Pränatale Medizin, Endokrinologie und Osteologie Hamburg GmbHamedes expertsHamburgDeutschland
  3. 3.Universitäts-Frauenklinik LübeckLübeckDeutschland

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