Klinische Neurologie pp 1-12 | Cite as
Multiple Sklerose: Klinik
Zusammenfassung
Die multiple Sklerose (MS) ist eine der häufigsten neurologischen Erkrankungen, für deren Ursache es bislang keine einheitliche Erklärung gibt. Die MS verläuft anfangs oft schubförmig-remittierend, später dann schubförmig- oder sekundär chronisch-progredient. Die klinischen Symptome sind aufgrund der Krankheitsmanifestation im gesamten zentralen Nervensystem äußerst heterogen. Insbesondere auch kognitive Defizite und das MS-assoziierte Fatigue-Syndrom sind in den letzten Jahren zunehmend in den Fokus der klinischen Forschung gelangt. Zudem werden durch die Möglichkeit einer symptomatischen Behandlung Symptome wie Spastik und autonome Störungen mehr berücksichtigt und wahrgenommen.
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