Encyclopedia of Parasitology

2016 Edition
| Editors: Heinz Mehlhorn

Clonorchis sinensis

  • Zhongdao WuEmail author
  • Heinz Mehlhorn
Reference work entry
DOI: https://doi.org/10.1007/978-3-662-43978-4_644


Greek: klon = branching system; orchis = testicle (the genus names describe that the testes are branching). Latin: sinensis = from China. English: Chinese liver fluke.

Geographic Distribution/Epidemiology

In East and South Asia, especially in China, Thailand, Korea, and Japan, about 50 millions of humans and some more dogs and cats are infected.

Morphology/Life Cycle

The dorsoventrally flattened adult worms (Figs. 1, 2, and 3) are hermaphrodites, reach a length of 10–20 mm and a width of 3–5 mm, and are able to stretch themselves considerably. These translucent worms live in the bile ducts of humans and fish-eating animals (e.g., also in dogs and cats), and their tegument does not contain hooks or scales (it is smooth). Characteristic for this species are the two testes, which lay in the terminal portion of the body and are branched. The anterior one shows 4 branches, the posterior one 5. Their single excretory ductules (vasa efferentia) unite themselves to form the vas deferens...
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  1. Pierkarski G (1965) Medical parasitology in plates (English translation). Springer, HeidelbergGoogle Scholar

Further Reading

  1. Chen D et al (2010) Epidemiological investigation of Clonorchis sinensis infection in freshwater fishes in the Pearl River Delta. Parasitol Res 107:835–839PubMedCrossRefGoogle Scholar
  2. Hong ST, Fang Y (2012) Clonorchis sinensis and clonorchiasis. An update. Parasitol Int 61:17–24PubMedCrossRefGoogle Scholar
  3. Keiser J, Utzinger J (2009) Food borne trematodiases. Clin Microbiol Rev 22:466–483PubMedPubMedCentralCrossRefGoogle Scholar
  4. Mehlhorn H et al (1983) Ultrastructural investigations of the effects of praziquantel on human trematodes from Asia (Clonorchis sinensis, Metagonimus yokogawai, Opisthorchis viverrini, Paragonimus westermani, Schistosoma japonicum). Drug Res 33:91–98Google Scholar
  5. Wu W et al (2012) A review of the control of clonorchiasis sinensis and Taenia solium taeniasis in China. Parasitol Res 111:1879–1884PubMedCrossRefGoogle Scholar
  6. Xiao SH et al (2011) Comparative effect of mebendazole, albendazole, tribendimidine and praziquantel in treatment of rats infected with Clonorchis sinensis. Parasitol Res 108:723–730PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Department of Parasitology, Zhongshan School of Medicine, Key Laboratory for Tropical Diseases Control, The Ministry of EducationSun Yat-sen University GuangzhouGuangzhouChina
  2. 2.Institut für Zoomorphologie, Zellbiologie und Parasitologie, Heinrich-Heine-UniversitätDüsseldorfGermany