Encyclopedia of Parasitology

2016 Edition
| Editors: Heinz Mehlhorn

Schistosoma: Integument/Surface Coat

  • Heinz MehlhornEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-662-43978-4_4488
The surface of the blood fluke, Schistosoma mansoni, has been analyzed very intensively in the past few years in order to find antigens for vaccination against this important parasite of man in the tropics (  Platyhelminthes/  Integument). As in all  digenea, all larval stages seem to have a  surface coat containing proteoglycans (Fig. 1). In the miracidium even the cilia are covered by a surface coat. Mother sporocysts of Schistosoma mansoni (like those of  Fasciola hepatica) show an amplification of the surface area by a mixture of branching folds and  microvilli. They are covered by a fuzzy surface coat. Vesicles at the base of the microvilli suggest the occurrence of  endocytosis. Rediae also have a surface coat. Although there is evidence that they are able to take up nutrients through the mouth into the small digestive system, absorption of nutrients by endocytosis through the  tegument has been observed for glucose, a polysaccharide, and amino acids.
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References

  1. Retra K, deWalick S, Schmitz M, Yazdanbakhsh M, Tielens AG, Brouwers JF, van Hellemond JJ (2015) The tegumental surface membranes of Schistosoma mansoni are enriched in parasite-specific phospholipid species. Int J Parasitol 45:629-36. http://www.ncbi.nlm.nih.gov/pubmed/25975668
  2. Smit CH, Homann A, van Hensbergen VP, Schramm G, Haas H, van Diepen A, Hokke CH (2015) Surface expression patterns of defined glycan antigens change during Schistosoma mansoni cercarial transformation and development of schistosomula. Glycobiology 7. pii: cwv066. http://www.ncbi.nlm.nih.gov/pubmed/26347524

Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Institut für ZoomorphologieZellbiologie und Parasitologie, Heinrich-Heine-UniversitätDüsseldorfGermany