Encyclopedia of Parasitology

2016 Edition
| Editors: Heinz Mehlhorn

Schistosoma Granuloma

  • Heinz MehlhornEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-662-43978-4_4314
Eggs of Schistosoma mansoni and S. japonicum introduce differently composed granuloma (e.g., in liver), although their adults live in the same blood vessel system (around the intestine of their hosts). In the center of the granulomas of both species one or several eggs are situated. In S. mansoni these eggs are surrounded mainly by eosinophilic granulocytes, while in the case of S. japonicum neutrophils enclose the centrally located eggs. Then follow (in both cases) collagen fibers from the inner to the outer side layers of macrophages of hepatic stellate cells and a final surrounding layer composed of a mixture of macrophages, neutrophils, and B- and T-cells (Fig. 1).
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Futher Reading

  1. Chuah C et al (2014) Cellular and chemokine-mediated regulation in schistosome-induced hepatic pathology. Trends Parasitol 30:141–150PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany