Syngamus Species
Name
Greek – syn = together, gamos = fusion. Latin – trachea = trachea, breathing tube. English – grape worm.
Geographic Distribution/Epidemiology
Worldwide in many bird and mammal species; in cases of farmed birds, often high prevalence rates have been observed.
Morphology/Life Cycle
- (a)
Syngamus trachea (Fig. 1). The adults of this so-called red tracheal worm measure 8 mm (males) in length and 20 mm (females), respectively, which live in permanent copulation attached at the tracheal wall, thus offering a Y-shaped aspect. Both sexes suck constantly blood at different places and thus appear reddish in shape. The females excrete the thick-walled 70–100 μm × 45–50 μm-sized eggs in an unembryonated stage (containing a morula of about 16 cells). The egg shell is characterized by thickenings at both poles (Fig. 1). The larva 3 is formed inside the egg shell within 1–2 weeks. If snails, earthworms, insects, or their larvae ingest such eggs, they may become accumulated there (larvae 3 may hatch, too). If birds ingest larvae 3 containing eggs or swallow such infested intermediate hosts, the larvae penetrate into the wall or directly into the body cavity. They reach the lung via the bloodstream or directly by entering the lung from the body cavity. From there they migrate into the lumen of the trachea, where they copulate and reach maturity within 1 week (Fig. 2). However, another week is needed until the first eggs are excreted.
- (b)
Syngamus (syn. Cyathostoma) bronchialis. This species parasitizes in the trachea and bronchioles of geese, ducks, and free-living birds. The males reach a length of about 6 mm, while the females are considerably longer (up to 3 cm). The adults do not live in permanent copulation, and the males appear whitish, while the females appear even dark red due to their permanent blood sucking. The further development is similar to that of S. trachea (Fig. 1).
- (c)
Syngamus (syn. Mammomonogamus) laryngeus occurs in the larynx of cattle and buffaloes in Asia, South and Central America, Sri Lanka, and the Philippines.
- (d)
Syngamus (syn. Mammomonogamus) nasicola is found in the nose cavities of ruminants in Africa and South and Central America.
- (e)
Mammomonogamus (syn. Syngamus) species of animals are also found in cats and in humans.
Life cycles of nematodes with facultative or obligate intermediate hosts. (a) Stephanurus dentatus adults (male 23 cm, female 34.5 cm) live in cysts of kidneys of swine (final host). (b) Porrocaecum ensicaudatum (female 45 cm) lives as adults in the small intestine of blackbirds. (c) Syngamus trachea (redworm, gapeworm); males (6 mm) and females (20 mm) suck blood in the trachea of poultry and are permanently attached to each other, thus giving a Y shape to the pair. 1 Eggs are mainly passed in urine (S. dentatus) or feces (other species) of final hosts. 2 On the soil, the eggs embryonate, leading to a first-stage larva (L1). In S. trachea development proceeds until the L3 is formed inside the egg, whereas in S. dentatus the L1 may leave the egg (2.1~2.2). Intermediate hosts may ingest the eggs (in P. caudatum it is obligatory), thus initiating the development of infectious larvae (L3), which may become accumulated in considerable numbers. 3 Infection of the final hosts always occurs via the oral route. This can be directly by ingestion of eggs containing a third-stage larva (S. trachea) or by uptake of free third-stage larvae (S. dentatus) with contaminated food or indirectly by ingestion of intermediate hosts containing infectious third-stage larvae (possible in all three species). BC buccal cavity, E esophagus, IN intestine, SH sheath (cuticle of first- or second-stage larva), UT uterus
Macrophoto of the opened trachea of a bird showing several of the blackish-appearing Syngamus trachea worms besides masses of coagulated blood
Symptoms of Disease (Syngamosis)
Especially young animals may become severely affected and show intense coughing, breathing problems (dyspnea seen by open mouth), tracheitis, apathia, loss of weight, anemia, death due to weakness, or suffocation. Adult animals mostly show only lower-graded symptoms.
Diagnosis
Microscopical inspection of the typical eggs (Fig. 1); (see nematode eggs of birds) after use of concentration methods (flotation, S.A.F.C.). Occurrence of adult worms in vomited material.
Infection
Oral uptake of infectious larva 3 containing eggs, larvae 3 or egg containing intermediate hosts such as earthworms, insects, snails, etc.
Prophylaxis
In stables, regular removement of feces.
Incubation Period
Three to five days.
Prepatent Period
Sixteen to twenty one days.
Patency
Several months (2–4).
Therapy
Benzimidazoles (e.g. flubendazole) had been proven to be highly efficacious as are macrocyclic lactones.
Further Readings
- Holand H et al (2013) Temporal and spatial variation in prevalence of the parasite Syngamus trachea. Parasitology 140:1275–1286PubMedCrossRefGoogle Scholar
- Krone O et al (2007) Specific status and pathogenicity of syngamid nematodes in bird species. J Helminthol 81:67–73PubMedCrossRefGoogle Scholar

