This system transports parasite proteins to the Maurer’s clefts (MC) – resembling Golgi- lamella – in Plasmodium-infected red blood cells via 2 ways:
- 1.
Vesicles are secreted from the lumen of the parasitophorus vacuole, which join the MC.
- 2.
Proteins are translocated across the vacuolar membrane into host cell cytosol and become associated with the cytoplasmic face of the MC.
Both processes are steered by a host-targeting signal (HT) and finally lead to transport of parasite protein into the host cell.
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© 2016 Springer-Verlag Berlin Heidelberg
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(2016). Secrotome. In: Mehlhorn, H. (eds) Encyclopedia of Parasitology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43978-4_2854
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DOI: https://doi.org/10.1007/978-3-662-43978-4_2854
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