Encyclopedia of Ophthalmology

Living Edition
| Editors: Ursula Schmidt-Erfurth, Thomas Kohnen

Keratoglobus Basic Science

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35951-4_542-2
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Synonyms

Definition

Keratoglobus is a rare, degenerative bilateral corneal disease characterized by corneal thinning and hemispherical protrusion that may lead to myopia (Lange and Gareis 2007).

Structure

Keratoglobus is characterized by thinning of the cornea from limbus to limbus (Wallang and Das 2013). Scleral thinning and minimal corneal scarring may also be involved. The cornea tends to be of normal or increased diameter with these physical changes (Karabatsas and Cook 1996). The eye will have normal to low intraocular pressure with a normal disk. Corneal edema is a rare complication of keratoglobus that increases the risk of rupture.

Functions

The cause of keratoglobus is unclear, and the pattern of corneal thinning tends to be unpredictable (Krachmer et al. 1984). Patients may report vision deterioration that affects their daily functioning. Keratoglobus does not cause blindness though.

Clinical Relevance

Keratoglobus is much more rare than...

Keywords

Contact Lens Corneal Edema Corneal Dystrophy Corneal Disease Vernal Keratoconjunctivitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Jones DH, Kirkness CM (2001) A new surgical technique for keratoglobus-tectonic lamellar keratoplasty followed by secondary penetrating keratoplasty. Cornea 20(8):885–887CrossRefPubMedGoogle Scholar
  2. Kodjikian L, Baillif S, Burillon C, Grange JD, Garweg JG (2004) Keratoglobus surgery: penetrating keratoplasty redux. Acta Ophthalmol Scand 82(5):625–627CrossRefPubMedGoogle Scholar
  3. Karabatsas CH, Cook SD (1996) Topographic analysis in pellucid marginal corneal degeneration and keratoglobus. Eye (Lond) 10(Pt4):451–455CrossRefGoogle Scholar
  4. Krachmer JH, Feder RS, Belin MW (1984) Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol 28(4):293–322CrossRefPubMedGoogle Scholar
  5. Lange GK, Gareis O (2007) Ophthalmology: a pocket textbook atlas, 2nd edn. Thieme, Stuttgart, pp 123–125Google Scholar
  6. Wallang BS, Das S (2013) Keratoglobus. Eye (Lond) 27(9):1004–1012CrossRefGoogle Scholar

Authors and Affiliations

  1. 1.University of Louisville OphthalmologyLouisvilleUSA