Encyclopedia of Biophysics

Living Edition
| Editors: Gordon Roberts, Anthony Watts, European Biophysical Societies

Quinone Cofactors

  • Victor L. Davidson
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35943-9_46-1

Definition

A quinone is a cyclic organic compound that contains two carbonyl (C=O) groups that are in the same aromatic ring. Quinone cofactors associate with enzymes and participate in electron transfer or catalysis or both. Quinone cofactors may also be formed by posttranslational modification of amino acid residues of proteins.

Basic Characteristics

Membrane-Bound Quinones

Quinone molecules within cell membranes (Fig. 1) act as electron transfer shuttles between proteins that function in respiration and photosynthesis. During mitochondrial electron transport, ubiquinone (also called Coenzyme Q) accepts electrons from both Complex I and Complex II and donates electrons to Complex III. Ubiquinone is also present in bacterial electron transfer chains, although some anaerobic respiratory chains use menaquinone instead. During photosynthetic electron transfer, plastoquinone transfers electrons from the photosystem II reaction center to the cytochrome bf complex.
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References

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Copyright information

© European Biophysical Societies' Association (EBSA) 2018

Authors and Affiliations

  1. 1.Burnett School of Biomedical Sciences, College of MedicineUniversity of Central FloridaOrlandoUSA