Encyclopedia of Biophysics

Living Edition
| Editors: Gordon Roberts, Anthony Watts, European Biophysical Societies

Relaxation Dispersion

  • John D. Persons
  • Shahid N. Khan
  • Rieko IshimaEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35943-9_342-1



In the NMR field, the term “relaxation dispersion” refers to the dependence of the spin relaxation rate on the magnetic field strength. Typically either the static field, B0, provided by the spectrometer or the radio-frequency (RF) field, B1, generated by the probe transmitter coil is varied over a wide range. The dependence of spin relaxation on B0 has been used to characterize relaxation mechanisms and spectral density functions (Koenig and Schillinger 1969; Kimmich 1979; Noack 1986). Its biophysics application includes paramagnetic interaction with proteins and residence times of water molecules in proteins to be obtained (Bertini et al. 1993; Halle and Denisov 1995). This B0-dependent relaxation dispersion experiment is also called “nuclear magnetic relaxation dispersion (NMRD),” “relaxometry,” or “field cycling,” in which the longitudinal relaxation rate, R1, is measured as a...

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Copyright information

© European Biophysical Societies' Association (EBSA) 2018

Authors and Affiliations

  • John D. Persons
    • 1
  • Shahid N. Khan
    • 1
  • Rieko Ishima
    • 1
    Email author
  1. 1.Department of Structural BiologyUniversity of Pittsburgh School of MedicinePittsburghUSA

Section editors and affiliations

  • Mitsu Ikura

There are no affiliations available