In the NMR field, the term “relaxation dispersion” refers to the dependence of the spin relaxation rate on the magnetic field strength. Typically either the static field, B0, provided by the spectrometer or the radio-frequency (RF) field, B1, generated by the probe transmitter coil is varied over a wide range. The dependence of spin relaxation on B0 has been used to characterize relaxation mechanisms and spectral density functions (Koenig and Schillinger 1969; Kimmich 1979; Noack 1986). Its biophysics application includes paramagnetic interaction with proteins and residence times of water molecules in proteins to be obtained (Bertini et al. 1993; Halle and Denisov 1995). This B0-dependent relaxation dispersion experiment is also called “nuclear magnetic relaxation dispersion (NMRD),” “relaxometry,” or “field cycling,” in which the longitudinal relaxation rate, R1, is measured as a...
- Kimmich R (1979) Field cycling in NMR relaxation spectroscopy: applications in biological, chemical and polymer physics. Bull Magn Reson 1:195–218Google Scholar