Encyclopedia of Biophysics

Living Edition
| Editors: Gordon Roberts, Anthony Watts, European Biophysical Societies

Proton-Coupled Electron Transfer

  • Jeffrey J. WarrenEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35943-9_18-1



Electron transfer (ET) and proton transfer (PT) are the two most fundamental chemical reactions. It has long been recognized that a great many ET reactions are associated with changes in protonation state. In general, this type of redox reaction is referred to as “proton-coupled electron transfer” or PCET. Original formulations of PCET reactions involved the transfer of a proton (H+) and an electron (e) from one donor to one acceptor. At present, it is known that PCET reactions can take a variety of forms. A few examples of PCET reactions include processes in which a H+ and an etransfer among one or more reactants in one or more kinetic steps; processes in which protons modulate ET, even if they do not transfer; and processes that involve multiple protons and/or...

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Copyright information

© European Biophysical Societies' Association (EBSA) 2018

Authors and Affiliations

  1. 1.Department of ChemistrySimon Fraser UniversityBurnabyCanada