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Controlled Release

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  • First Online:
Encyclopedia of Polymeric Nanomaterials

Synonyms

Controlled release; Sustained release; Timed release

Definition

Controlled release is the tailorable delivery of compounds (e.g., drugs, proteins, fertilizers, nutrients, and other biologically active agents) at an effective level in response to time and stimuli (e.g., pH, temperature, enzymes, UV light, magnetic fields, osmosis).

Introduction

The field of controlled release began in the early 1950s with the development of polymeric systems that were capable of releasing oral drugs in a tailorable manner [1]. Soon after, controlled release of marine antifoulants was achieved in the 1950s [2] followed by fertilizers in the 1970s [3]. Release of loaded agents can be varied by many different factors including the release environment, diffusion, molecular weight and solubility of drugs, pore size, and degradation of the polymeric carriers [1–11]. Controlled release can be valuable in areas such as cosmetics, pesticides, agriculture, pharmaceuticals, and food science. This entry...

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References

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Author information

Authors and Affiliations

  1. Theranostic Macromolecules Research Center, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do, 440-746, Republic of Korea

    Cong Truc Huynh & Doo Sung Lee

  2. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA

    Cong Truc Huynh

Authors
  1. Cong Truc Huynh
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  2. Doo Sung Lee
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Corresponding author

Correspondence to Doo Sung Lee .

Editor information

Editors and Affiliations

  1. Center for Fiber and Textile Science, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto, Japan

    Shiro Kobayashi

  2. Max Planck Institute for Polymer Research, Mainz, Germany

    Klaus Müllen

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Huynh, C.T., Lee, D.S. (2015). Controlled Release. In: Kobayashi, S., Müllen, K. (eds) Encyclopedia of Polymeric Nanomaterials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29648-2_314

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