Definition
The hot plate test involves placement of a rat or mouse on a heated surface (usually ≥50 °C) and measuring the latency (in seconds) to licking of a hindpaw or jumping. The hot plate test, which employs a fixed temperature, has largely been supplanted by what is termed the “Hargreaves Test” in which a rat or mouse is placed on a glass surface and the animal’s hindpaw is heated from below by a radiant heat source. Latency from stimulus to withdrawal of the paw is measured in this test.
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© 2013 Springer-Verlag Berlin Heidelberg
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(2013). Hot Plate Test (Assay). In: Gebhart, G.F., Schmidt, R.F. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28753-4_200958
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DOI: https://doi.org/10.1007/978-3-642-28753-4_200958
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-28752-7
Online ISBN: 978-3-642-28753-4
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