The KRAS gene is the human cellular homologue of a transforming gene isolated from the Kirsten rat sarcoma virus. It belongs to the mammalian RAS gene family, which name derived from “rat sarcoma” and which most studied members are KRAS, HRAS, and NRAS. These genes encode proteins with a molecular mass of 21 kD and the three are homologues of rodent sarcoma virus genes that have transforming abilities.
Approved symbol from the HUGO Gene Nomenclature Committee (HGNC) database: KRAS
Previous name: v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homologue. Previous symbol: KRAS2
Also known as KRAS1...