Colon Cancer Carcinogenesis in Human and in Experimental Animal Models
Living reference work entry
Colon cancer (often subsumed under the term colorectal cancer (CRC), Fig. 1) develops as a result of the pathologic transformation of normal colonic epithelium to an adenomatous polyp and ultimately an invasive cancer. The multistep development requires years and possibly decades and is accompanied by a number of genetic alterations.
KeywordsUlcerative Colitis Familial Adenomatous Polyposis Lynch Syndrome Colonic Carcinogen Colitic Cancer
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© Springer-Verlag Berlin Heidelberg 2015